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Biology of Reproduction, Vol 1, 197-199, Copyright © 1969 by Society for the Study of Reproduction

The Effect of Coagulating Gland Secretion on the Coagulating Activity of Cowper's Secretion in the Rat

R. G. HART 1

1 Department of Biology, Slippery Rock State College, Slippery Rock, Pennsylvania


In studies carried out on the rat (four different samples of nonpooled accessory fluid per experiment (N = 4)) coagulating secretion at pH 5.9 displayed minimal activity in coagulating vesicular substrate but potentiated the coagulation reaction involving Cowper's and seminal vesicle secretion. This effect could not be mimicked by prostate, ampullary, or epididymal secretions. The active molecule in coagulating secretion was heat-labile and nondialyzable. Further studies suggest that the potentiating effect observed resulted from prior activation of the vesicular substrate for Cowper's secretion by coagulating secretion.

Submitted on February 7, 1969






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Copyright © 1969 by the Society for the Study of Reproduction.