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Biology of Reproduction, Vol 10, 321-326, Copyright © 1974 by Society for the Study of Reproduction

Adenylate Cyclase Activity of Porcine Corpora Lutea

R. N. ANDERSEN 1, F. L. SCHWARTZ 1, , and L. C. ULBERG 1

1 Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, and Reproductive Physiology Research Laboratory, North Carolina State University, Raleigh, North Carolina


Adenylate cyclase of porcine luteal tissue has been studied in relation to luteal regression. The level of adenylate cyclase activity was greater in tissue obtained at Days 12 or 14 of a cycle than in tissue from Days 16 or 17. The enzyme was responsive to added LH at Days 12 or 14 of the estrous cycle, but failed to respond to LH in tissue obtained at Days 16 or 17 of a cycle.

A decline in adenylate cyclase activity and loss of responsiveness to LH appear to be correlated with the onset of luteal regression.






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Copyright © 1974 by the Society for the Study of Reproduction.