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Biology of Reproduction, Vol 11, 50-55, Copyright © 1974 by Society for the Study of Reproduction
1 Laboratory of Human Reproduction and Reproductive Biology and Department of Anatomy,
Harvard Medical School, Boston, Massachusetts 02115 Antiserum to rat deciduoma produced in the rabbit cross-reacted with mouse deciduoma
extract in agar gel double diffusion test. The results of immunoelectrophoresis revealed
that the mouse deciduoma extract contained one antigen specific to deciduoma. This
antigen has a mobility similar to the antigen found in rat deciduoma. Intraluminal injection
of the antiserum to the mouse uterus suppressed deciduoma formation. These results
suggest that mechanisms of decidualization in both species may involve similar cellular
changes in producing new substances in the decidualized tissue.
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