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Biology of Reproduction, Vol 11, 436-439, Copyright © 1974 by Society for the Study of Reproduction

The In Vitro Effects of Oxytocin and Vasopressin on Spontaneous Contractility of the Mouse Cauda Epididymidis

JOSÉ HIB 1

1 Centro Latinoamericano de Perinatología y Desarrollo Humano Hospital de Clínicas—Piso 16, Montevideo, Uruguay


The effects of oxytocin and vasopressin on the motility of mice cauda epididymidis were studied in vitro by isometric recording of contractions. Contractility of the cauda was evaluated by measuring the baseline tension (in mg), the frequency (number of contractions/min), and the amplitude (in mg). Results were analyzed for statistical significance by using analysis of variance.

Oxytocin and vasopressin produced an increase in the frequency and amplitude of contractions. In addition, vasopressin caused an incremental rise in the baseline tension.

These results suggest that both neurohypophyseal hormones are involved in the mechanism causing a sudden release of sperm from the cauda epididymidis into the vas deferens at the time of ejaculation.

 Accepted on June 25, 1974




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Copyright © 1974 by the Society for the Study of Reproduction.