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Biology of Reproduction, Vol 11, 509-512, Copyright © 1974 by Society for the Study of Reproduction

Absence of Neutral Proteinase Activity in Rat Ovarian Follicle Walls at Ovulation

EARL L. PARR 1

1 Laboratories of Human Reproduction and Reproductive Biology, Harvard Medical School, 45 Shattuck Street, Boston Massachusetts 02115


We were unable to detect neutral proteinase activity in rat ovarian follicle walls near the time of ovulation. The proteolytic activity of cathepsins at acid pH was readily detected, as was the neutral proteinase of polymorphonuclear leukocytes. It thus appears that the rupture of the ovarian follicle at ovulation is not mediated by a proteolytic enzyme stored in the tissue.

Accepted on July 17, 1974




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 Endocr. Rev.Home page
T. E. Curry Jr. and K. G. Osteen
The Matrix Metalloproteinase System: Changes, Regulation, and Impact throughout the Ovarian and Uterine Reproductive Cycle
Endocr. Rev., August 1, 2003; 24(4): 428 - 465.
[Abstract] [Full Text] [PDF]


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Copyright © 1974 by the Society for the Study of Reproduction.