| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Biology of Reproduction, Vol 12, 317-324, Copyright © 1975 by Society for the Study of Reproduction
1 Department of Anatomy, Monash University, Melbourne, Australia, and Division of Endocrinology, Department of
Medicine, University of Washington, Seattle, Washington. U.S.A. The peritubular tissue of the human testis has been examined by light and electron microscopy in
biopsies from 5 normal men, 10 untreated men with hypogonadotrophic hypogonadism and 52 men with
oligospermia or azoospermia. In the normal, the lamina propria of the tubules consisted of two
alternating layers of collagen fibres and myoid cells to whose surface a thin layer of basement
membrane-like material and microfibrils was closely applied. In hypogonadotrophic hypogonadism, the
immature seminiferous cords were surrounded by less well defined layers of myoid cells and collagen
fibres and the myoid cell surfaces did not exhibit the coating of basement membrane-like material and
microfibrils. In the patients with azoospermia or oligospermia, three patterns of organization of the lamina
propria were apparent: (1) The normal appearance. (2) Increase in thickness of the layers of collagen
fibres. (3) Disorganization of the lamina propria by a marked increase in the thickness of either the
basement membrane-like material or microfibrillar layers immediately adjacent to the myoid cells. The
third pattern was found in patients with severely damaged testes such as in seminiferous tubule
hyalinization. The observations indicate that the thickening of the lamina propria of the seminiferous
tubules seen in some damaged testes does not involve the appearance of new components but widening
of existing structures.
This article has been cited by other articles:
|
|
 |
|
  S. Mazaud Guittot, A. Verot, F. Odet, M.-A. Chauvin, and B. le Magueresse-Battistoni A comprehensive survey of the laminins and collagens type IV expressed in mouse Leydig cells and their regulation by LH/hCG Reproduction, April 1, 2008; 135(4): 479 - 488. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Le Magueresse-Battistoni Serine proteases and serine protease inhibitors in testicular physiology: the plasminogen activation system Reproduction, December 1, 2007; 134(6): 721 - 729. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. K. Lee and D. N. R. Veeramachaneni Subchronic Exposure to Low Concentrations of Di-n-Butyl Phthalate Disrupts Spermatogenesis in Xenopus laevis Frogs Toxicol. Sci., April 1, 2005; 84(2): 394 - 407. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D Govender, Y Sing, and R Chetty Sertoli cell nodules in the undescended testis: a histochemical, immunohistochemical, and ultrastructural study of hyaline deposits J. Clin. Pathol., August 1, 2004; 57(8): 802 - 806. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Middendorff, D. Muller, S. Wichers, A. F. Holstein, and M. S. Davidoff Evidence for Production and Functional Activity of Nitric Oxide in Seminiferous Tubules and Blood Vessels of the Human Testis J. Clin. Endocrinol. Metab., December 1, 1997; 82(12): 4154 - 4161. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Z. Kahsai, G. C. Enders, S. Gunwar, C. Brunmark, J. Wieslander, R. Kalluri, J. Zhou, M. E. Noelken, and B. G. Hudson Seminiferous Tubule Basement Membrane. COMPOSITION AND ORGANIZATION OF TYPE IV COLLAGEN CHAINS, AND THE LINKAGE OF alpha 3(IV) AND alpha 5(IV) CHAINS J. Biol. Chem., July 4, 1997; 272(27): 17023 - 17032. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. Le Magueresse-Battistoni, G. Pernod, L. Kolodie, A.-M. Morera, and M. Benahmed Tumor Necrosis Factor-{alpha} Regulates Plasminogen Activator Inhibitor-1 in Rat Testicular Peritubular Cells Endocrinology, March 1, 1997; 138(3): 1097 - 1105. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
