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Biology of Reproduction, Vol 12, 590-598, Copyright © 1975 by Society for the Study of Reproduction
1 Department of Poultry Science, Cornell University, Ithaca, N.Y. 14853 and Department of Physiology and
Biochemistry, The University, Whiteknights, Reading RG62AJ, England The concentrations of estradiol, estrone, progesterone and LH are reported for blood samples taken
at different intervals during the ovulatory cycle of the domestic fowl. In general there appears to exist a
consistent relationship between peaks of estradiol and estrone concentrations, on the one hand, and the
progesterone peaks, on the other hand. These peaks of estrogen end progesterone precede ovulation by 4-7 hours. Ovulation does, however,
occur occasionally in the absence of estrogen peaks and some estrogen peaks appear not to be related to
ovulation. In samples taken at 20-min intervals at about the time of the expected progesterone peak it was
found that the progesterone concentrations varied in a pulsatile fashion whereas estrogen and LH concentrations did not, but showed a smooth peak. Experiments with different doses of estradiol 17
and progesterone failed to show either an inhibitory
or facilitory effect of estradiol on spontaneous or progesterone-induced ovulation.
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