Biol Reprod Lalor Postdoctoral Fellowships -- Application Deadline January 15, 2009
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by ANDERSON, M. L.
Right arrow Articles by HAYASHIDA, T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by ANDERSON, M. L.
Right arrow Articles by HAYASHIDA, T.
Agricola
Right arrow Articles by ANDERSON, M. L.
Right arrow Articles by HAYASHIDA, T.

Biology of Reproduction, Vol 13, 499-504, Copyright © 1975 by Society for the Study of Reproduction

Immunofluorescence Studies on the Localization of Relaxin in the Corpus Luteum of the Pregnant Rat

MARY L. ANDERSON 1, JOHN A. LONG 1, , and T. HAYASHIDA 1

1 Department of Anatomy, University of California, San Francisco, California 94143


We have used 17 day pregnant Long-Evans rats to demonstrate, utilizing indirect fluorescent antibody methods, that relaxin is present in luteal cells of the ovary. Furthermore, this technique revealed that the highest concentration of relaxin is localized in the juxtanuclear area of the cell, presumably over the Golgi region.

The role of granular cells of the uterine metrial gland as a source of relaxin in the pregnant rat is still not clarified. Using the indirect fluorescent antibody technique only one experiment out of six demonstrated the presence of relaxin in the granular cells of the metrial gland. However, other investigators claim to have localized relaxin in these granular cells by the fluorescent antibody technique. Failure to obtain such consistent results in our studies may have been a result of low concentrations of relaxin in the granular cells and/or the presence of an immunochemically different relaxin molecule in these cells.

 Submitted on March 4, 1975
Accepted on August 8, 1975






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1975 by the Society for the Study of Reproduction.