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Biology of Reproduction, Vol 14, 219-221, Copyright © 1976 by Society for the Study of Reproduction
1 Department of Anatomy and Reproductive Biology,
John A. Burns School of Medicine,
Honolulu, Hawaii 96822 The hamster adrenal gland was found to be a new and very potent source of "sperm motility
factor" (SMF); the activity of SMF in adrenal extracts was approximately 100 to 200 times that in
hamster blood serum. Hamster epididymal spermatozoa incubated with adrenal extracts became
capacitated. as shown by their ability to fertilize cumulus-free eggs. Like the SMF in human blood
serum, the hamster adrenal SMF has a low molecular weight (about 100 to 200) and is heat-stable.
Note:
ACKNOWLEDGMENTS
One of us (B.D.B.) was supported by Research Fellowships from the Population Council and the Ford
Foundation, and the work was also supported by
grants from the Population Council and the United
States Public Health Service (HD-03402).
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