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Biology of Reproduction, Vol 14, 314-316, Copyright © 1976 by Society for the Study of Reproduction

Further Observation on Implantation in Prepuberal Rats Treated with Gonadotrophins

J. T. WU 1

1 Worcester Foundation for Experimental Biology, Shrewsbury, Massachusetts 01545


The possibility of delayed implantation in prepuberal rats treated with gonadotrophins was examined. They were injected with 8, 10 or 12 IU PMS at 29 or 30 days of age, followed 52 h later by 1.0 or 1.2 IU HCG, and allowed to mate. On Day 7 of pregnancy (Day 1 = sperm in the vagina) all rats which had been injected with 8 IU PMS at 30 days (followed by HCG) showed normal implantation; while in the other groups, normal implantation occurred in 33 to 71 percent of the rats, with the remaining in delayed implantation.

Note:
ACKNOWLEDGMENT This study was supported by a grant (HD 03003) from the National Institute of Child Health and Human Development, NIH, and a grant from the Ford Foundation, both awarded to Dr. M. C. Chang, whose interest in this study was greatly appreciated.

Submitted on August 6, 1975
Accepted on November 11, 1975






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Copyright © 1976 by the Society for the Study of Reproduction.