Biol Reprod Keystone Symposia Conference on Frontiers in Reproductive Biology & Regulation of Fertility.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by BARTKE, A.
Right arrow Articles by DALTERIO, S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by BARTKE, A.
Right arrow Articles by DALTERIO, S.
Agricola
Right arrow Articles by BARTKE, A.
Right arrow Articles by DALTERIO, S.

Biology of Reproduction, Vol 15, 90-93, Copyright © 1976 by Society for the Study of Reproduction

Effects of Prolactin on the Sensitivity of the Testis to LH

A. BARTKE 1, and S. DALTERIO 1

1 Worcester Foundation for Experimental Biology, Shrewsbury, Massachusetts 01545


Treatment of adult hypophysectomized rats with ectopic pituitary homografts caused a significant increase in testicular sensitivity to LH, as determined from measurements of peripheral testosterone levels 2.5 h after the injection of a single large dose of LH. Increased testicular responsiveness to acute LH stimulation was also observed after treatment with grafts or prolactin (PRL) combined with a chronic LH treatment, and in some instances, after treatment with PRL or chronic LH alone. It is suggested that PRL may have a role in sensitizing the testis to LH in the course of normal sexual maturation.

Note:
ACKNOWLEDGMENTS This work was supported by NICHHD through a Career Development Award 5 K04 HD70369 (A.B.) and a grant 5 R0l HD06867. We thank NIAMDD for the generous supply of PRL, LH and FSH, Ms. C. Roberson for performing PRL radioimmunoassays and Dr. B. V. Caldwell for antiserum to testosterone.

Submitted on February 24, 1976
Accepted on March 29, 1976




This article has been cited by other articles:


Home page
 EndocrinologyHome page
R. W. Steger, V. Chandrashekar, W. Zhao, A. Bartke, and N. D. Horseman
Neuroendocrine and Reproductive Functions in Male Mice with Targeted Disruption of the Prolactin Gene
Endocrinology, September 1, 1998; 139(9): 3691 - 3695.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1976 by the Society for the Study of Reproduction.