Biol Reprod 2009 SSR Annual Meeting Abstracts
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Biology of Reproduction, Vol 16, 600-604, Copyright © 1977 by Society for the Study of Reproduction

Surface Ultrastructural Changes in Granulosa Cells of Atretic Follicles

J. J. PELUSO 1, R. W. STEGER 1, , and E. S. E. HAFEZ 1

1 Reproductive Physiology Laboratories, C. S. Mott Center for Human Growth and Development, Wayne State University School of Medicine, Detroit, Michigan 48201


In nonatretic antral ovarian follicles of the rat, adjacent granulosa cells were in close contact, spherical in shape, and possessed irregular cytoplasmic evaginations. As the follicle became atretic, the intercellular space between the granulosa cells increased and these cells became flattened and lost their cytoplasmic evaginations. In advanced stages of atresia aggregates of granulosa cells were attached to follicular basement membrane.

Note:
ACKNOWLEDGMENT Thanks are due to Mr. Phil Sherman for his excellent technical assistance.

Submitted on August 31, 1976
Accepted on January 19, 1977






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Copyright © 1977 by the Society for the Study of Reproduction.