Biol Reprod Keystone Symposia Conference on Frontiers in Reproductive Biology & Regulation of Fertility.
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Biology of Reproduction, Vol 20, 1111-1114, Copyright © 1979 by Society for the Study of Reproduction

Glycogen Levels in the Rat Myometrium at the End of Pregnancy and Immediately Postpartum

C. S. CHEW 1, and G. A. RINARD 1

1 Department of Physiology, Emory University, Atlanta, Georgia 30322


The glycogen content of the myometrium of the pregnant rat was found to increase dramatically just prior to parturition. At this time glycogen concentrations were similar to those in skeletal muscle and much greater than those in uteri from rats on Days 18 and 20 of pregnancy and in uteri from nonpregnant, cycling rats or ovariectomized, estrogen treated rats. Parturition, when allowed to occur naturally or when induced by oxytocin infusion, significantly reduced myometrial glycogen. These results suggest that glycogen may serve as an important source of energy in the maintenance of uterine contractions during labor. A large store of glycogen may be of particular importance when blood flow in the uterus is reduced by strong myometrial contractions.

Note:
ACKNOWLEDGMENTS We would like to thank Ms. A. W. Hunter for her expert technical assistance and Ms. M. Olson for typing the manuscript.

Submitted on November 20, 1978
Accepted on February 9, 1979






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Copyright © 1979 by the Society for the Study of Reproduction.