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Biology of Reproduction, Vol 21, 373-377, Copyright © 1979 by Society for the Study of Reproduction

Stimulation of Endogenous RNA Polymerase I Activity in the Mouse Oocyte after PMSG Treatment

G. P.M. MOORE 1, and SUE LINTERN-MOORE 2

1 Ian Clunies Ross Animal Research Laboratory, C.S.I.R.O., Division of Animal Production, Blacktown, N.S.W. 2148, Australia
2 School of Biological Sciences Macquarie University, North Ryde, N.S.W. 2113, Australia


The pattern of RNA synthesis in oocytes of the mouse ovary changes after administration of pregnant mare serum gonadotropin. The activities of endogenous, nucleolar RNA polymerases increase, specifically in multilaminar, preantral follicles. This effect is not mediated through an increase in estrogen production.

Note:
ACKNOWLEDGMENTS This work was supported, in part, by a Queen Elizabeth II Fellowship (G.P.M.M.) and a Clive and Vera Ramaciotti Foundation Grant (S.L-M.).

Submitted on January 10, 1979
Accepted on April 16, 1979






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Copyright © 1979 by the Society for the Study of Reproduction.