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Biology of Reproduction, Vol 21, 413-417, Copyright © 1979 by Society for the Study of Reproduction

Effect of Various Exposure Times to Hyperthermia and Hypothermia on Spontaneous Contractions of the Adult Rabbit Isolated Testicular Capsule

JOSEPH R. DAVIS 1, and ARTHUR M. HOROWITZ 1

1 Department of Pharmacology and Therapeutics, Loyola University of Chicago Stritch School of Medicine, Maywood, illinois 60153


Spontaneous contractions of the adult rabbit isolated testicular capsule were found to be influenced by moderate hyperthermic and hypothermic temperature changes. An increase in organ bath temperature from a normal scrotal temperature of 37°C to 42°C for an exposure period greater than 15 min resulted in irreversible changes in spontaneous contractions of the testicular capsule. However, complete recovery of spontaneous contractions, of the testicular capsule, which had been inhibited by an exposure of 40°C for 120 min, occurred when the tissue was returned to 37°C. In contrast, decreases in organ bath temperatures from 37°C to 32°C for up to 120 min produced a progressive increase in amplitude of contractions. Corresponding exposures of the isolated testicular capsule for the same time periods at 16°C resulted in complete but reversible cessation of spontaneous contractions.

Submitted on November 6, 1978
Accepted on April 16, 1979







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Copyright © 1979 by the Society for the Study of Reproduction.