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Biology of Reproduction, Vol 21, 433-437, Copyright © 1979 by Society for the Study of Reproduction

Levels of Deoxycorticosterone and 21-Hydroxy-5agr-pregnane-3,20-dione in the Peripheral Circulation of the Prepartum and Postpartum Mare

J. L. FLEEGER 1, P. G. HARMS 1, E. L. DUNN 1, , and D. T. ATKINS 1

1 Department of Animal Science, Texas Agricultural Experiment Station, Texas A&M University, College Station, Texas 77843


Blood samples were collected from 8 mares for 10 days before and 2 days after parturition. The steroid, 21-hydroxy-5agr-pregnane-3,20-dione, was tentatively identified in the peripheral circulation of the mare by its cross reactivity after acetylation with an antiserum and by its elution pattern on microcelite and Sephadex LH-20 column chromatography. The presence of deoxycorticosterone was determined in the same manner. Deoxycorticosterone and 21-hydroxy-5agr-pregnane-3,20-dione were elevated from 30 to 6 h (P<0.05) before parturition. The level of these steroids was lower (P<0.05) from 18 to 42 h postpartum. The source of these steroids is not known and their function is not established.

Submitted on February 1, 1979
Accepted on April 16, 1979






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Copyright © 1979 by the Society for the Study of Reproduction.