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Biology of Reproduction, Vol 21, 709-713, Copyright © 1979 by Society for the Study of Reproduction

Tissue Specificity of Porcine Zona Pellucida Antigen(s) Tested by Radioimmunoassay

V. S. PALM 1, A. G. SACCO 1, F. N. SYNER 1, , and M. G. SUBRAMANIAN 1

1 Department of Gynecology and Obstetrics, Wayne State University School of Medicine, The C. S. Mott Center for Human Growth and Development, Detroit, Michigan 48201


The tissue specificity of porcine zona pellucida antigen(s) and the monospecificity of antibodies to isolated porcine zonae pellucidae were examined by radioimmunoassay. No zona immunoreactivity was detected in 22 porcine tissues and fluids examined with the exception of ovary. These data strongly indicate that porcine zonae pellucidae contain a specific antigen(s).

Note:
ACKNOWLEDGMENTS This work was supported in part by a grant from the Deutsche Forschungsgemeinschaft, Bonn-Bad Godesberg, Federal Republic of Germany, No. Pa 200/3-4) to VSP.

Submitted on February 26, 1979
Accepted on May 23, 1979




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