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Biology of Reproduction, Vol 22, 202-204, Copyright © 1980 by Society for the Study of Reproduction

Absence of a Prelabor Relaxin Surge in Women

JOHN QUAGLIARELLO , DINAH S. LUSTIG , BERNARD G. STEINETZ 1, , and GERSON WEISS 2

1 Department of Obstetrics and Gynecology and Department of Physiology, New York University School of Medicine, New York, New York 10016 and Ciba-Geigy Corporation, Ardsley, New York 10502
2 Dept. of Obstetrics and Gynecology, New York University School of Medicine, 530 First Avenue, New York, NY 10016.


Serum immunoreactive relaxin concentrations were measured in 74 women sampled within 7 days prior to the onset of spontaneous term labor and again during active spontaneous labor. No significant differences between antepartum and intrapartum values were noted. In contrast to rodents and pigs, no prelabor elevations in relaxin secretion occur in women.

Submitted on September 12, 1979
Accepted on November 6, 1979




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