Biol Reprod Keystone Symposia Conference on Frontiers in Reproductive Biology & Regulation of Fertility.
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Biology of Reproduction, Vol 22, 297-306, Copyright © 1980 by Society for the Study of Reproduction

Changes in the Testes and Epididymides of Rabbits Following Long Term Vasectomy or Vasocystostomy: Correlation with Results of Vasovasostomy

RUSSELL H. HOOKER 1

1 Worcester Foundation for Experimental Biology, Shrewsbury, Massachusetts 01545


The purpose of the present study was to compare the effect of vasectomy (sperm obstruction) with vasocystostomy (sperm diversion) on the testes and epididymides of rabbits and to correlate pathologic changes with success or failure of vasovasostomy to restore fertility.

Vasovasostomy restored fertility to 36% of rabbits following vasectomy and to 100% of those in which sperm had been previously diverted by vasocystostomy. Pathologic changes were found in 73% of testes and 42% of epididymides following sperm obstruction, but there were no changes in the testis and only rare changes in the epididymis following sperm diversion.

It is concluded that vasocystostomy is a more physiological form of surgical contraception than conventional vasectomy in the rabbit.

Note:
ACKNOWLEDGMENTS I wish to thank Pathology Associates Laboratory, Inc. for preparation of the histological material, Drs. Robert S. Harper and Martin Dym for their independent interpretations of the microscopic sections and Drs. J. McCracken, M. C. Chang and C. Longcope for criticism of the manuscript.

Submitted on September 12, 1979
Accepted on October 29, 1979




This article has been cited by other articles:


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 J AndrolHome page
K. Steger, M. Slavov, K. Failing, W. Weidner, and M. Bergmann
Effect of Vasectomy on Sperm Nuclear Chromatin Condensation in the Rabbit
J Androl, March 1, 2005; 26(2): 289 - 295.
[Abstract] [Full Text] [PDF]


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Copyright © 1980 by the Society for the Study of Reproduction.