Biol Reprod Keystone Symposia Conference on Frontiers in Reproductive Biology & Regulation of Fertility.
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Biology of Reproduction, Vol 23, 1054-1059, Copyright © 1980 by Society for the Study of Reproduction

Dolichol Concentration and Biosynthesis in Rat Testis and Epididymis

JOHN C. WENSTROM 1, and DAVID W. HAMILTON 1

1 Department of Anatomy, University of Minnesota, Minneapolis, Minnesota 55455


The concentration and synthesis of dolichol was studied in testis and epididymis. In the rat, dolichol concentration is highest in the caput and corpus epididymidis, and concentrations in testis and all parts of the epididymis are higher than in rat liver. Uptake of 2-[14C]-mevalonic acid into dolichols separated by high performance liquid chromatography mirrors dolichol concentration in the organs studied, with greatest incorporation into dolichols in the corpus epididymidis.

Submitted on July 14, 1980
Accepted on October 13, 1980






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Copyright © 1980 by the Society for the Study of Reproduction.