Biol Reprod Lalor Postdoctoral Fellowships -- Application Deadline January 15, 2009
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by JORDAN, A. W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by JORDAN, A. W.
Agricola
Right arrow Articles by JORDAN, A. W.

Biology of Reproduction, Vol 24, 245-248, Copyright © 1981 by Society for the Study of Reproduction

Changes in Ovarian beta-Adrenergic Receptors During the Estrous Cycle of the Rat

ALEXANDER W. JORDAN 1

1 Division of Drug Biology, Pharmaceutical Research and Testing, Food and Drug Administration, Washington, D.C. 20204


Scatchard plot analyses of [3H]-dihydroalprenolol binding to rat ovarian membranes revealed that the rat ovary contains a single class of specific, high affinity beta-adrenergic receptors which vary significantly during the estrous cycle. Receptor concentrations are highest during proestrus, fall to 50% of proestrus levels in the morning of estrus (P<0.001), then increase to near proestrus levels during metestrus and diestrus. There is no change in receptor affinity during the estrous cycle (KD = 2.2 ± 0.1 x 10-9 M). These results indicate that ovarian function may be influenced directly by catecholamines of either a neural or adrenal origin.

Note:
ACKNOWLEDGMENTS I would like to thank Sylvia Colson for her expert technical assistance.

Submitted on August 20, 1980
Accepted on October 21, 1980






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1981 by the Society for the Study of Reproduction.