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Biology of Reproduction, Vol 24, 846-851, Copyright © 1981 by Society for the Study of Reproduction

Serum Placental Lactogen in Mice in Relation to Day of Gestation and Number of Conceptuses

EDITH MARKOFF 1, and FRANK TALAMANTES 1

1 Division of Natural Sciences, University of California, Santa Cruz, California 95064


Placental lactogen (PL) has been measured throughout gestation by radioreceptor assay. Serum mouse PL (mPL) levels were low at the beginning of gestation, peaked at Day 10, and returned to low levels again by Day 13. From Day 13 until term, mPL levels remained low. No circadian rhythm in mPL levels was seen over two different 24 h periods. Mouse PL levels were correlated with the number of conceptuses in an animal from Days 9 to 18 of gestation.

Note:
ACKNOWLEDGMENTS We would like to thank A. Levy for his excellent technical assistance and L. Ogren for critical review of this manuscript. This work was supported by a Faculty Research Committee Grant from the University of California and by grant NIH-3-SO6 RR08132-0251 GRC to F. Talamantes.

Submitted on November 4, 1980
Accepted on January 21, 1981






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Copyright © 1981 by the Society for the Study of Reproduction.