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Biology of Reproduction, Vol 3, 55-60, Copyright © 1970 by Society for the Study of Reproduction
1 Wisconsin Regional Primate Research Center and Departments of
Physiology and Zoology, University of Wisconsin,
Madison, Wisconsin 53706 The urinary excretion of estrogens was determined in six rhesus monkeys (Macaca
mulatta) during and after pregnancy. Of the three "classical" estrogens, only estrone
was present in measurable amounts, mostly as glucosiduronate. The urinary concentration of this steroid increased progressively during the last 8-9 weeks of pregnancy and
showed a marked rise during the week immediately preceding parturition. This was
followed by a sudden decrease in steroid excretion on the day before or on the day of
delivery. Estriol was detected in small amounts in all the animals, mostly as sulfate.
Estradiol-17
was present but could not be accurately measured because of the interference of an unidentified compound which had chromatographic properties similar to
those of estradiol. Three days after parturition, the urinary levels of these estrogens
declined to nonpregnancy values.
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