Biol Reprod
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Day, J. R.
Right arrow Articles by Lu, J. K.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Day, J. R.
Right arrow Articles by Lu, J. K.
Agricola
Right arrow Articles by Day, J. R.
Right arrow Articles by Lu, J. K.

Biology of Reproduction, Vol 38, 1019-1026, Copyright © 1988 by Society for the Study of Reproduction

ARTICLES

Male stimulation of luteinizing hormone surge, progesterone secretion and ovulation in spontaneously persistent-estrous, aging rats

JR Day, TH Morales and JK Lu
Department of Obstetrics/Gynecology, UCLA School of Medicine 90024-1740.

In aging, persistently estrous (PE) female rats, there are no estrous cycles or cyclic increases in luteinizing hormone (LH) secretion, but the sexual receptivity to the male is consistently maintained. We recently reported that caging and mating with fertile males elicits an LH surge followed by ovulation in aging PE rats. The present study examined the relationship between the LH surge, the increase in progesterone (P) secretion and ovulation in PE females exposed to males, and assessed whether intromission was essential for the male- induced pre-ovulatory LH surge. PE rats were implanted with intra- atrial cannulae. Six to eight days later, these females were individually caged with a fertile male and repeatedly sampled (once every 30 or 60 min) between 1400 and 1900 h for assays of plasma LH and P. Sexual behavior of the female was recorded and correlated with the changes in plasma LH and P values. Similar experiments were also performed on cannulated PE rats with their vaginal orifice blocked with adhesive tape during the caging and sampling session. In both experiments, over 90% of the PE females displayed a high degree of lordosis response to mounting by the male, and over 60% of those sexually receptive PE females exhibited an LH surge followed by ovulation. The male-induced preovulatory LH surge occurred in PE females without actual intromission. Caging with fertile males also elicited a marked increase in plasma P concentrations in PE rats and in PE females prevented from experiencing intromission.(ABSTRACT TRUNCATED AT 250 WORDS)


This article has been cited by other articles:


Home page
 Biol. Reprod.Home page
H.-W. Tsai, P. S. LaPolt, A. P. Olcott, and J. K.H. Lu
Temporal Changes Occur in the Neuroendocrine Control of Gonadotropin Secretion in Aging Female Rats: Role of Progesterone
Biol Reprod, September 1, 2004; 71(3): 845 - 852.
[Abstract] [Full Text] [PDF]

Home page
 Exp. Biol. Med.Home page
B.-Y. Chern, Y.-H. J. Chen, L.-S. Hong, and P. S. LaPolt
Ovarian Steroidogenic Responsiveness to Exogenous Gonadotropin Stimulation in Young and Middle-Aged Female Rats
Experimental Biology and Medicine, September 1, 2000; 224(4): 285 - 291.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1988 by the Society for the Study of Reproduction.