Biol Reprod
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Segerson, E. C.
Right arrow Articles by Stuart, L. D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Segerson, E. C.
Right arrow Articles by Stuart, L. D.
Agricola
Right arrow Articles by Segerson, E. C.
Right arrow Articles by Stuart, L. D.

Biology of Reproduction, Vol 38, 1085-1091, Copyright © 1988 by Society for the Study of Reproduction

ARTICLES

Uterine-specific proteins in luminal secretions of swine leukocyte antigen-inbred miniature swine with cystic endometrial hyperplasia

EC Segerson, JR Diehl and LD Stuart
Department of Animal Science, North Carolina A&T State University, Greensboro 27411.

Uterine-specific proteins were evaluated in luminal secretions of Swine Leukocyte Antigen (SLA)-inbred miniature swine with cystic endometrial hyperplasia (CEH) by polyacrylamide gel electrophoresis (PAGE) and Sephacryl S-200 chromatography. CEH and non-CEH (NCEH) pigs (n = 23) were killed on Days 4, 9, and 15 of the estrous cycle (estrus = Day 0) and reproductive tracts were excised for collection of serum and uterine luminal protein. Uterine luminal protein was greater (p less than 0.05) on Day 9 than on Days 4 and 15 (42.9 vs. 6.1 and 29.4 mg, respectively) for CEH pigs and Days 4, 9, and 15 (8.5, 10.1, and 25.6 mg, respectively) for NCEH pigs. The presence of the uterine-specific acidic and basic proteins, as revealed by PAGE, was affected (p less than 0.025) by day of the cycle and CEH condition. All Day 15 NCEH pigs (4 of 4) produced the complete profile of these proteins, whereas none of the uterine protein samples representing other treatment groups contained them. Some minor acidic protein components were present in cystic fluids from CEH pigs, but these fluids lacked the typical uterine-specific proteins. PAGE analysis of Sephacryl S-200 fractions from uterine fluids of Day 15 NCEH pigs revealed the uterine-specific proteins in fractions IV (Mr 40,000) and V (Mr 15,000). The results of the investigation demonstrate an impairment in the secretion of uterine- specific proteins in cyclic SLA miniature swine with cystic endometrial hyperplasia.




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1988 by the Society for the Study of Reproduction.