Biol Reprod
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by REEVES, J. J.
Right arrow Articles by SCHALLY, A. V.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by REEVES, J. J.
Right arrow Articles by SCHALLY, A. V.
Agricola
Right arrow Articles by REEVES, J. J.
Right arrow Articles by SCHALLY, A. V.

Biology of Reproduction, Vol 4, 88-92, Copyright © 1971 by Society for the Study of Reproduction

Changes in Pituitary Responsiveness to Luteinizing Hormone-Releasing Hormone (LH-RH) in Anestrous Ewes Pretreated with Estradiol Benzoate

JERRY J. REEVES 1, AKIRA ARIMURA 1, , and ANDREW V. SCHALLY 1

1 Endocrine and Polypeptide Laboratories, Veterans Administration Hospital and Department of Medicine, Tulane University School of Medicine, New Orleans, Louisiana 70140


Mature, whitefaced ewes maintained in an anestrous reproductive state were divided into four groups which received oil, 25 µg estradiol benzoate (EB), 250 µg EB, and 500 µg EB, respectively. Twenty hours after pretreatment with EB, 3.0 µg LH-RH was administered intracarotidly. The highest LH value after LH-RH administration minus the preinjection LH value yielded Dgr LH in nanograms per milliliter which was used as the experimental index of pituitary responsiveness to LH-RH. Pretreatment with 250 µg EB increased baseline levels of LH. Doses of 250 and 500 µg EB augmented increased LH release due to LH-RH administration as compared to the oil and 25 µg EB pretreated ewes. The present results support the hypothesis that part of the LH-release augmenting effect of estrogens may be due to an increase in pituitary responsiveness to LH-RH.

Submitted on November 18, 1970




This article has been cited by other articles:


Home page
 Biol. Reprod.Home page
B. Levavi-Sivan, J. Biran, and E. Fireman
Sex Steroids Are Involved in the Regulation of Gonadotropin-Releasing Hormone and Dopamine D2 Receptors in Female Tilapia Pituitary
Biol Reprod, October 1, 2006; 75(4): 642 - 650.
[Abstract] [Full Text] [PDF]

Home page
 Biol. Reprod.Home page
N. J. Place, K. E. Holekamp, C. L. Sisk, M. L. Weldele, E. M. Coscia, C. M. Drea, and S. E. Glickman
Effects of Prenatal Treatment with Antiandrogens on Luteinizing Hormone Secretion and Sex Steroid Concentrations in Adult Spotted Hyenas, Crocuta crocuta
Biol Reprod, November 1, 2002; 67(5): 1405 - 1413.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
A. Caraty, C. Fabre-Nys, B. Delaleu, A. Locatelli, G. Bruneau, F. J. Karsch, and A. Herbison
Evidence That the Mediobasal Hypothalamus Is the Primary Site of Action of Estradiol in Inducing the Preovulatory Gonadotropin Releasing Hormone Surge in the Ewe
Endocrinology, April 1, 1998; 139(4): 1752 - 1760.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
A. V. Schally, A. Arimura, and A. J. Kastin
Hypothalamic Regulatory Hormones: At least nine substances from the hypothalamus control the secretion of pituitary hormones
Science, January 26, 1973; 179(4071): 341 - 350.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1971 by the Society for the Study of Reproduction.