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Biology of Reproduction, Vol 43, 694-697, Copyright © 1990 by Society for the Study of Reproduction
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CA Lingwood, PA Quinn, S Wilansky, A Nutikka, HL Ruhnke and RB Miller
Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada.
Sulfoglycolipids are ubiquitous components of the male germ cell membrane. Sulfogalactoglycerolipid (SGG) is restricted to mammalian cells and has recently been implicated in sperm/egg interactions. Mycoplasma infections have been implicated in infertility in a variety of species, including humans. Four such species-specific mycoplasmas, Ureaplasma urealyticum and Mycoplasma hominis (humans), Mycoplasma pulmonis (rodents), and Ureaplasma diversum (cattle) are not shown to specifically recognize SGG and the sphingolipid counterpart, sulfogalactosyl ceramide. This glycolipid receptor binding may relate to the reproductive pathogenesis of these organisms.
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