Biol Reprod Lalor Postdoctoral Fellowships -- Application Deadline January 15, 2009
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Mora, O. A.
Right arrow Articles by Sanchez-Criado, J. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Mora, O. A.
Right arrow Articles by Sanchez-Criado, J. E.
Agricola
Right arrow Articles by Mora, O. A.
Right arrow Articles by Sanchez-Criado, J. E.

Biology of Reproduction, Vol 51, 920-925, Copyright © 1994 by Society for the Study of Reproduction

ARTICLES

Hormonal pattern of the pheromonal restoration of cyclic activity in aging irregularly cycling and persistent-estrus female rats

OA Mora, MM Cabrera and JE Sanchez-Criado
Departamento de Fisiologia, Facultad de Medicina, Universidad Complutense, Madrid, Spain.

This study reports the hormonal pattern of pheromonal restoration of cyclic activity (PRCA) in irregularly cycling (IC) and in anovulatory persistent-estrus (PE) aging female middle-aged Wistar rats. Hypothalamic content of LHRH and plasma levels of LH, FSH, estradiol (E2), and progesterone (P) were measured by RIA methods, and prolactin (PRL) was examined by ELISA in 1) normal four-day cycling rats, 2) saline-treated IC and PE rats, and 3) IC and PE rats treated with sprays of male urine (50 microliters every 10 min for 1 h on only one day, at a distance of 1 cm from the nostrils). Group 1 showed low levels of LHRH and high levels of LH, FSH, E2, P, and PRL in the afternoon of proestrus (PR). In group 2, the pattern was not cyclical and the levels of the hormones were higher than basal for the cyclic rats, except for P, which was lower. Group 3 showed a depletion of the hypothalamic LHRH and an increase in plasma LH, FSH, E2, Pm, and PRL. FSH, E2, and P showed the strongest rise, leading to an elevated ratio of FSH to LH. Four-day estrous cycles reappeared in urine-treated rats on the succeeding days. The cyclic behavior of the PRCA hormones was, qualitatively, the same as in the normally cycling rats. According to the results, the origin of the PRCA effect is an olfactory input to the hypophysiotropic area of the hypothalamus.(ABSTRACT TRUNCATED AT 250 WORDS)




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1994 by the Society for the Study of Reproduction.