Biol Reprod Lalor Postdoctoral Fellowships -- Application Deadline January 15, 2009
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
 QUICK SEARCH:   [advanced]


     


This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow My Folders
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Strauss, J. F.
Right arrow Articles by Kiriakidou, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Strauss, J. F., 3rd
Right arrow Articles by Kiriakidou, M.
Agricola
Right arrow Articles by Strauss, J. F.
Right arrow Articles by Kiriakidou, M.

Biology of Reproduction, Vol 54, 303-311, Copyright © 1996 by Society for the Study of Reproduction


REVIEWS

Placental steroid hormone synthesis: unique features and unanswered questions

JF Strauss 3rd, F Martinez and M Kiriakidou
Department of Obstetrics and Gynecology University of Pennsylvania, Philadelphia 19104, USA.

Despite the amazing diversity of placental architecture across species, a number of common elements can be found, including the ability of all placentae to synthesize and metabolize steroid hormones; the assignment of steroidogenic activities to specific trophoblast phenotypes; the use of novel mechanisms to control expression of steroidogenic enzyme genes, which differ from those employed in the adrenal cortex and gonads; and interactions with the maternal and fetal compartments encompassing supply of steroid hormone precursors as well as regulatory influences of maternal ovarian and pituitary hormones and fetal adrenal cortical steroids.


This article has been cited by other articles:


Home page
EndocrinologyHome page
N. Yivgi-Ohana, N. Sher, N. Melamed-Book, S. Eimerl, M. Koler, P. R. Manna, D. M. Stocco, and J. Orly
Transcription of Steroidogenic Acute Regulatory Protein in the Rodent Ovary and Placenta: Alternative Modes of Cyclic Adenosine 3', 5'-Monophosphate Dependent and Independent Regulation
Endocrinology, February 1, 2009; 150(2): 977 - 989.
[Abstract] [Full Text] [PDF]


Home page
EndocrinologyHome page
C. Lopez-Garcia, A. J. Lopez-Contreras, A. Cremades, M. T. Castells, F. Marin, F. Schreiber, and R. Penafiel
Molecular and Morphological Changes in Placenta and Embryo Development Associated with the Inhibition of Polyamine Synthesis during Midpregnancy in Mice
Endocrinology, October 1, 2008; 149(10): 5012 - 5023.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
J. Geyer, B. Doring, K. Meerkamp, B. Ugele, N. Bakhiya, C. F. Fernandes, J. R. Godoy, H. Glatt, and E. Petzinger
Cloning and Functional Characterization of Human Sodium-dependent Organic Anion Transporter (SLC10A6)
J. Biol. Chem., July 6, 2007; 282(27): 19728 - 19741.
[Abstract] [Full Text] [PDF]


Home page
ReproductionHome page
R. G Lea, P. Wooding, I. Stewart, L. T Hannah, S. Morton, K. Wallace, R. P Aitken, J. S Milne, T. R Regnault, R. V Anthony, et al.
The expression of ovine placental lactogen, StAR and progesterone-associated steroidogenic enzymes in placentae of overnourished growing adolescent ewes
Reproduction, April 1, 2007; 133(4): 785 - 796.
[Abstract] [Full Text] [PDF]


Home page
Mol. Endocrinol.Home page
N. Sher, N. Yivgi-Ohana, and J. Orly
Transcriptional Regulation of the Cholesterol Side Chain Cleavage Cytochrome P450 Gene (CYP11A1) Revisited: Binding of GATA, Cyclic Adenosine 3',5'-Monophosphate Response Element-Binding Protein and Activating Protein (AP)-1 Proteins to a Distal Novel Cluster of cis-Regulatory Elements Potentiates AP-2 and Steroidogenic Factor-1-Dependent Gene Expression in the Rodent Placenta and Ovary
Mol. Endocrinol., April 1, 2007; 21(4): 948 - 962.
[Abstract] [Full Text] [PDF]


Home page
Mol. Pharmacol.Home page
M. Grube, K. Kock, S. Karner, S. Reuther, C. A. Ritter, G. Jedlitschky, and H. K. Kroemer
Modification of OATP2B1-Mediated Transport by Steroid Hormones
Mol. Pharmacol., November 1, 2006; 70(5): 1735 - 1741.
[Abstract] [Full Text] [PDF]


Home page
J. Clin. Endocrinol. Metab.Home page
H. al Kandari, N. Katsumata, S. Alexander, and M. A. Rasoul
Homozygous Mutation of P450 Side-Chain Cleavage Enzyme Gene (CYP11A1) in 46, XY Patient with Adrenal Insufficiency, Complete Sex Reversal, and Agenesis of Corpus Callosum
J. Clin. Endocrinol. Metab., August 1, 2006; 91(8): 2821 - 2826.
[Abstract] [Full Text] [PDF]


Home page
J EndocrinolHome page
L D. Valle, V Toffolo, A Nardi, C Fiore, P Bernante, R Di Liddo, P. Parnigotto, and L Colombo
Tissue-specific transcriptional initiation and activity of steroid sulfatase complementing dehydroepiandrosterone sulfate uptake and intracrine steroid activations in human adipose tissue.
J. Endocrinol., July 1, 2006; 190(1): 129 - 139.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
A. A. Mathias, J. Hitti, and J. D. Unadkat
P-glycoprotein and breast cancer resistance protein expression in human placentae of various gestational ages
Am J Physiol Regulatory Integrative Comp Physiol, October 1, 2005; 289(4): R963 - R969.
[Abstract] [Full Text] [PDF]


Home page
Endocr. Rev.Home page
A. H. Payne and D. B. Hales
Overview of Steroidogenic Enzymes in the Pathway from Cholesterol to Active Steroid Hormones
Endocr. Rev., December 1, 2004; 25(6): 947 - 970.
[Abstract] [Full Text] [PDF]


Home page
Mol. Cell. Biol.Home page
S. R. Bair and S. H. Mellon
Deletion of the Mouse P450c17 Gene Causes Early Embryonic Lethality
Mol. Cell. Biol., June 15, 2004; 24(12): 5383 - 5390.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Endocrinol. Metab.Home page
B. Ugele, M. V. St-Pierre, M. Pihusch, A. Bahn, and P. Hantschmann
Characterization and identification of steroid sulfate transporters of human placenta
Am J Physiol Endocrinol Metab, February 1, 2003; 284(2): E390 - E398.
[Abstract] [Full Text] [PDF]


Home page
Mol. Endocrinol.Home page
M. Ben-Zimra, M. Koler, and J. Orly
Transcription of Cholesterol Side-Chain Cleavage Cytochrome P450 in the Placenta: Activating Protein-2 Assumes the Role of Steroidogenic Factor-1 by Binding to an Overlapping Promoter Element
Mol. Endocrinol., August 1, 2002; 16(8): 1864 - 1880.
[Abstract] [Full Text] [PDF]


Home page
Mol Hum ReprodHome page
F. Debieve and K. Thomas
Control of the human inhibin {alpha} chain promoter in cytotrophoblast cells differentiating into syncytium
Mol. Hum. Reprod., March 1, 2002; 8(3): 262 - 270.
[Abstract] [Full Text] [PDF]


Home page
EndocrinologyHome page
G. J. Pepe, M. G. Burch, and E. D. Albrecht
Localization and Developmental Regulation of 11{beta}-Hydroxysteroid Dehydrogenase-1 and -2 in the Baboon Syncytiotrophoblast
Endocrinology, January 1, 2001; 142(1): 68 - 80.
[Abstract] [Full Text] [PDF]


Home page
J. Clin. Endocrinol. Metab.Home page
M. Bonenfant, C. H. Blomquist, P. R. Provost, R. Drolet, P. D’Ascoli, and Y. Tremblay
Tissue- and Site-Specific Gene Expression of Type 2 17{beta}-Hydroxysteroid Dehydrogenase: In Situ Hybridization and Specific Enzymatic Activity Studies in Human Placental Endothelial Cells of the Arterial System
J. Clin. Endocrinol. Metab., December 1, 2000; 85(12): 4841 - 4850.
[Abstract] [Full Text]


Home page
J. Clin. Endocrinol. Metab.Home page
M. Malatesta, F. Mannello, F. Luchetti, F. Marcheggiani, L. Condemi, S. Papa, and G. Gazzanelli
Prostate-Specific Antigen Synthesis and Secretion by Human Placenta: A Physiological Kallikrein Source during Pregnancy
J. Clin. Endocrinol. Metab., January 1, 2000; 85(1): 317 - 321.
[Abstract] [Full Text]


Home page
EndocrinologyHome page
J. Arensburg, A. H. Payne, and J. Orly
Expression of Steroidogenic Genes in Maternal and Extraembryonic Cells During Early Pregnancy in Mice
Endocrinology, November 1, 1999; 140(11): 5220 - 5232.
[Abstract] [Full Text]


Home page
EndocrinologyHome page
X. Chu, C. J. Corbin, M. A. Kaminski, and A. J. Conley
Unique Regulation of CYP17 Expression in the Trophectoderm of the Preattachment Porcine Blastocyst
Endocrinology, February 1, 1999; 140(2): 632 - 640.
[Abstract] [Full Text]


Home page
Clin. Chem.Home page
F. Mannello, M. Malatesta, E. Fusco, G. Bianchi, A. Cardinali, and G. Gazzanelli
Biochemical Characterization and Immunolocalization of Prostate-specific Antigen in Human Term Placenta
Clin. Chem., August 1, 1998; 44(8): 1735 - 1737.
[Full Text] [PDF]


Home page
J. Clin. Endocrinol. Metab.Home page
M. V. J. Mustonen, V. V. Isomaa, T. Vaskivuo, J. Tapanainen, M. H. Poutanen, F. Stenbäck, R. K. Vihko, and P. T. Vihko
Human 17{beta}-Hydroxysteroid Dehydrogenase Type 2 Messenger Ribonucleic Acid Expression and Localization in Term Placenta and in Endometrium during the Menstrual Cycle
J. Clin. Endocrinol. Metab., April 1, 1998; 83(4): 1319 - 1324.
[Abstract] [Full Text]


Home page
J. Lipid Res.Home page
A. K. Hatzopoulos, A. Rigotti, R. D. Rosenberg, and M. Krieger
Temporal and spatial pattern of expression of the HDL receptor SR-BI during murine embryogenesis
J. Lipid Res., March 1, 1998; 39(3): 495 - 508.
[Abstract] [Full Text]


Home page
EndocrinologyHome page
F. Martinez, M. Kiriakidou, and J. F. Strauss III
Structural and Functional Changes in Mitochondria Associated with Trophoblast Differentiation: Methods to Isolate Enriched Preparations of Syncytiotrophoblast Mitochondria
Endocrinology, May 1, 1997; 138(5): 2172 - 2183.
[Abstract] [Full Text] [PDF]


Home page
EndocrinologyHome page
N. Pilon, I. Daneau, C. Brisson, J.-F. Ethier, J. G. Lussier, and D. W. Silversides
Porcine and Bovine Steroidogenic Acute Regulatory Protein (StAR) Gene Expression during Gestation
Endocrinology, March 1, 1997; 138(3): 1085 - 1091.
[Abstract] [Full Text] [PDF]




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1996 by the Society for the Study of Reproduction.