Biol Reprod
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Smith, C. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Smith, C. L.
Agricola
Right arrow Articles by Smith, C. L.

Biology of Reproduction, Vol 58, 627-632, Copyright © 1998 by Society for the Study of Reproduction

REVIEWS

Cross-talk between peptide growth factor and estrogen receptor signaling pathways

CL Smith
Department of Cell Biology, Baylor College of Medicine, Houston, Texas 77030-3498, USA. carolyns@bcm.tmc.edu

The classical receptor for estradiol is a member of a super-family of nuclear receptors that function as hormone-regulated transcription factors. The ability of the estrogen receptor (ER)-alpha to activate target gene transcription is mediated by two transcriptional activation functions (AF): AF-1 located in the amino-terminal domain and AF-2 found in the carboxyl-terminal portion of the molecule. The ligand binding domain overlaps AF-2, and upon estrogen binding this region undergoes a conformational change that enables it to contribute to the receptor's transcriptional activity. ER activation is accompanied by increased phosphorylation, and in the absence of ligand, activators of protein kinase A or inhibitors of protein phosphatases are able to stimulate ER-dependent gene expression. More importantly, polypeptide growth factors, such as epidermal growth factor (EGF) and insulin-like growth factor-I (IGF-I), also stimulate the ER's transcriptional activity in an estrogen-independent manner. The AF-1 domain appears to be required for activation by EGF and IGF-I, and point mutation of a single phosphorylation site located within this domain inhibits the ability of growth factor to activate the ER. Thus, steroid receptor function may be regulated by estrogenic ligands as well as by pathway "cross-talk" from membrane receptors for growth factors.


This article has been cited by other articles:


Home page
 J Mol EndocrinolHome page
R. S Thomas, N. Sarwar, F. Phoenix, R C. Coombes, and S. Ali
Phosphorylation at serines 104 and 106 by Erk1/2 MAPK is important for estrogen receptor-{alpha} activity
J. Mol. Endocrinol., April 1, 2008; 40(4): 173 - 184.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
M. B. Martin, R. Reiter, M. Johnson, M. S. Shah, M. C. Iann, B. Singh, J. K. Richards, A. Wang, and A. Stoica
Effects of Tobacco Smoke Condensate on Estrogen Receptor-{alpha} Gene Expression and Activity
Endocrinology, October 1, 2007; 148(10): 4676 - 4686.
[Abstract] [Full Text] [PDF]

Home page
 Clin. Cancer Res.Home page
J. Jiang, N. Sarwar, D. Peston, E. Kulinskaya, S. Shousha, R. C. Coombes, and S. Ali
Phosphorylation of Estrogen Receptor-{alpha} at Ser167 Is Indicative of Longer Disease-Free and Overall Survival in Breast Cancer Patients
Clin. Cancer Res., October 1, 2007; 13(19): 5769 - 5776.
[Abstract] [Full Text] [PDF]

Home page
 Cancer Res.Home page
K. Dhar, S. Banerjee, G. Dhar, K. Sengupta, and S. K. Banerjee
Insulin-like Growth Factor-1 (IGF-1) Induces WISP-2/CCN5 via Multiple Molecular Cross-talks and Is Essential for Mitogenic Switch by IGF-1 Axis in Estrogen Receptor-Positive Breast Tumor Cells
Cancer Res., February 15, 2007; 67(4): 1520 - 1526.
[Abstract] [Full Text] [PDF]

Home page
 Ann. N. Y. Acad. Sci.Home page
M. KLOUCHE
Estrogens in Human Vascular Diseases
Ann. N.Y. Acad. Sci., November 1, 2006; 1089(1): 431 - 443.
[Abstract] [Full Text] [PDF]

Home page
 Endocr. Rev.Home page
U. Ohnemus, M. Uenalan, J. Inzunza, J.-A. Gustafsson, and R. Paus
The Hair Follicle as an Estrogen Target and Source
Endocr. Rev., October 1, 2006; 27(6): 677 - 706.
[Abstract] [Full Text] [PDF]

Home page
 ReproductionHome page
V. Stabile, M. Russo, and P. Chieffi
17{beta}-Estradiol induces Akt-1 through estrogen receptor-{beta} in the frog (Rana esculenta) male germ cells.
Reproduction, September 1, 2006; 132(3): 477 - 484.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
W. Yan, A. A. Wiley, R. A. D. Bathgate, A.-L. Frankshun, S. Lasano, B. D. Crean, B. G. Steinetz, C. A. Bagnell, and F. F. Bartol
Expression of LGR7 and LGR8 by Neonatal Porcine Uterine Tissues and Transmission of Milk-Borne Relaxin into the Neonatal Circulation by Suckling
Endocrinology, September 1, 2006; 147(9): 4303 - 4310.
[Abstract] [Full Text] [PDF]

Home page
 ReproductionHome page
W. Yan, P. L Ryan, F. F Bartol, and C. A Bagnell
Uterotrophic effects of relaxin related to age and estrogen receptor activation in neonatal pigs.
Reproduction, May 1, 2006; 131(5): 943 - 950.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
J. G. W. Fleming, T. E. Spencer, S. H. Safe, and F. W. Bazer
Estrogen Regulates Transcription of the Ovine Oxytocin Receptor Gene through GC-Rich SP1 Promoter Elements
Endocrinology, February 1, 2006; 147(2): 899 - 911.
[Abstract] [Full Text] [PDF]

Home page
 The OncologistHome page
L. Giacinti, P. P. Claudio, M. Lopez, and A. Giordano
Epigenetic information and estrogen receptor alpha expression in breast cancer.
Oncologist, January 1, 2006; 11(1): 1 - 8.
[Abstract] [Full Text] [PDF]

Home page
 J Mol EndocrinolHome page
S Zhang, X Li, R Burghardt, R Smith III, and S H Safe
Role of estrogen receptor (ER) {alpha} in insulin-like growth factor (IGF)-I-induced responses in MCF-7 breast cancer cells
J. Mol. Endocrinol., December 1, 2005; 35(3): 433 - 447.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Interv.Home page
J. M. Hall and D. P. McDonnell
Coregulators in Nuclear Estrogen Receptor Action: From Concept to Therapeutic Targeting
Mol. Interv., December 1, 2005; 5(6): 343 - 357.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
T. Takahashi, M. Ohmichi, J. Kawagoe, C. Ohshima, M. Doshida, T. Ohta, M. Saitoh, A. Mori-Abe, B. Du, H. Igarashi, et al.
Growth Factors Change Nuclear Distribution of Estrogen Receptor-{alpha} via Mitogen-Activated Protein Kinase or Phosphatidylinositol 3-Kinase Cascade in a Human Breast Cancer Cell Line
Endocrinology, September 1, 2005; 146(9): 4082 - 4089.
[Abstract] [Full Text] [PDF]

Home page
 Exp. Biol. Med.Home page
I. Woclawek-Potocka, T. J. Acosta, A. Korzekwa, M. M. Bah, M. Shibaya, K. Okuda, and D. J. Skarzynski
Phytoestrogens Modulate Prostaglandin Production in Bovine Endometrium: Cell Type Specificity and Intracellular Mechanisms
Experimental Biology and Medicine, May 1, 2005; 230(5): 326 - 333.
[Abstract] [Full Text] [PDF]

Home page
 Mol Hum ReprodHome page
A. P. Ponnampalam, G. C. Weston, A. C. Trajstman, B. Susil, and P. A.W. Rogers
Molecular classification of human endometrial cycle stages by transcriptional profiling
Mol. Hum. Reprod., December 1, 2004; 10(12): 879 - 893.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
J. N. Holloway, S. Murthy, and D. El-Ashry
A Cytoplasmic Substrate of Mitogen-Activated Protein Kinase Is Responsible for Estrogen Receptor-{alpha} Down-Regulation in Breast Cancer Cells: The Role of Nuclear Factor-{kappa}B
Mol. Endocrinol., June 1, 2004; 18(6): 1396 - 1410.
[Abstract] [Full Text] [PDF]

Home page
 Biol. Reprod.Home page
R. W.S. Chan, K. E. Schwab, and C. E. Gargett
Clonogenicity of Human Endometrial Epithelial and Stromal Cells
Biol Reprod, June 1, 2004; 70(6): 1738 - 1750.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
K. Ikeda, S. Ogawa, T. Tsukui, K. Horie-Inoue, Y. Ouchi, S. Kato, M. Muramatsu, and S. Inoue
Protein Phosphatase 5 Is a Negative Regulator of Estrogen Receptor-Mediated Transcription
Mol. Endocrinol., May 1, 2004; 18(5): 1131 - 1143.
[Abstract] [Full Text] [PDF]

Home page
 Biol. Reprod.Home page
H. Cardenas and W. F. Pope
Attenuation of Estrogenic Effects by Dihydrotestosterone in the Pig Uterus Is Associated with Downregulation of the Estrogen Receptors
Biol Reprod, February 1, 2004; 70(2): 297 - 302.
[Abstract] [Full Text] [PDF]

Home page
 Biol. Reprod.Home page
W. B. Nothnick, X. Zhang, and H.-E Zhou
Steroidal Regulation of Uterine Edema and Tissue Inhibitors of Metalloproteinase (TIMP)-3 Messenger RNA Expression Is Altered in TIMP-1-Deficient Mice
Biol Reprod, February 1, 2004; 70(2): 500 - 508.
[Abstract] [Full Text] [PDF]

Home page
 Clin. Cancer Res.Home page
M. M. Desouki and B. G. Rowan
Src Kinase and Mitogen-Activated Protein Kinases in the Progression from Normal to Malignant Endometrium
Clin. Cancer Res., January 15, 2004; 10(2): 546 - 555.
[Abstract] [Full Text] [PDF]

Home page
 FASEB J.Home page
A. M. FOWLER, N. SOLODIN, M. T. PREISLER-MASHEK, P. ZHANG, A. V. LEE, and E. T. ALARID
Increases in estrogen receptor-{alpha} concentration in breast cancer cells promote serine 118/104/106-independent AF-1 transactivation and growth in the absence of estrogen
FASEB J, January 1, 2004; 18(1): 81 - 93.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
B. Chen, D. Zhang, and J. W. Pollard
Progesterone Regulation of the Mammalian Ortholog of Methylcitrate Dehydratase (Immune Response Gene 1) in the Uterine Epithelium during Implantation through the Protein Kinase C Pathway
Mol. Endocrinol., November 1, 2003; 17(11): 2340 - 2354.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
D. Chen, M. J. Lucey, F. Phoenix, J. Lopez-Garcia, S. M. Hart, R. Losson, L. Buluwela, R. C. Coombes, P. Chambon, P. Schar, et al.
T:G Mismatch-specific Thymine-DNA Glycosylase Potentiates Transcription of Estrogen-regulated Genes through Direct Interaction with Estrogen Receptor {alpha}
J. Biol. Chem., October 3, 2003; 278(40): 38586 - 38592.
[Abstract] [Full Text] [PDF]

Home page
 Biol. Reprod.Home page
K. D. Carpenter, C. A. Gray, T. M. Bryan, T. H. Welsh Jr., and T. E. Spencer
Estrogen and Antiestrogen Effects on Neonatal Ovine Uterine Development
Biol Reprod, August 1, 2003; 69(2): 708 - 717.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
M. Dutertre and C. L. Smith
Ligand-Independent Interactions of p160/Steroid Receptor Coactivators and CREB-Binding Protein (CBP) with Estrogen Receptor-{alpha}: Regulation by Phosphorylation Sites in the A/B Region Depends on Other Receptor Domains
Mol. Endocrinol., July 1, 2003; 17(7): 1296 - 1314.
[Abstract] [Full Text] [PDF]

Home page
 Biol. Reprod.Home page
R. Thuillier, Y. Wang, and M. Culty
Prenatal Exposure to Estrogenic Compounds Alters the Expression Pattern of Platelet-Derived Growth Factor Receptors {alpha} and {beta} in Neonatal Rat Testis: Identification of Gonocytes as Targets of Estrogen Exposure
Biol Reprod, March 1, 2003; 68(3): 867 - 880.
[Abstract] [Full Text] [PDF]

Home page
 JNCI J Natl Cancer InstHome page
G. Konecny, G. Pauletti, M. Pegram, M. Untch, S. Dandekar, Z. Aguilar, C. Wilson, H.-M. Rong, I. Bauerfeind, M. Felber, et al.
Quantitative Association Between HER-2/neu and Steroid Hormone Receptors in Hormone Receptor-Positive Primary Breast Cancer
J Natl Cancer Inst, January 15, 2003; 95(2): 142 - 153.
[Abstract] [Full Text] [PDF]

Home page
 J. Nutr.Home page
M. B. Martin and A. Stoica
Insulin-Like Growth Factor-I and Estrogen Interactions in Breast Cancer
J. Nutr., December 1, 2002; 132(12): 3799S - 3801.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
G. Min, H. Kim, Y. Bae, L. Petz, and J. K. Kemper
Inhibitory Cross-talk between Estrogen Receptor (ER) and Constitutively Activated Androstane Receptor (CAR). CAR INHIBITS ER-MEDIATED SIGNALING PATHWAY BY SQUELCHING p160 COACTIVATORS
J. Biol. Chem., September 6, 2002; 277(37): 34626 - 34633.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
C. E. Gargett, M. Zaitseva, K. Bucak, S. Chu, P. J. Fuller, and P. A. W. Rogers
17{beta}-Estradiol Up-Regulates Vascular Endothelial Growth Factor Receptor-2 Expression in Human Myometrial Microvascular Endothelial Cells: Role of Estrogen Receptor-{alpha} and -{beta}
J. Clin. Endocrinol. Metab., September 1, 2002; 87(9): 4341 - 4349.
[Abstract] [Full Text] [PDF]

Home page
 Biol. Reprod.Home page
S. Eimerl and J. Orly
Regulation of Steroidogenic Genes by Insulin-Like Growth Factor-1 and Follicle-Stimulating Hormone: Differential Responses of Cytochrome P450 Side-Chain Cleavage, Steroidogenic Acute Regulatory Protein, and 3{beta}-Hydroxysteroid Dehydrogenase/Isomerase in Rat Granulosa Cells
Biol Reprod, September 1, 2002; 67(3): 900 - 910.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
H. Lee and W. Bai
Regulation of Estrogen Receptor Nuclear Export by Ligand-Induced and p38-Mediated Receptor Phosphorylation
Mol. Cell. Biol., August 15, 2002; 22(16): 5835 - 5845.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
C. Qi, J. Chang, Y. Zhu, A. V. Yeldandi, S. M. Rao, and Y.-J. Zhu
Identification of Protein Arginine Methyltransferase 2 as a Coactivator for Estrogen Receptor alpha
J. Biol. Chem., August 2, 2002; 277(32): 28624 - 28630.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
K. M. Robertson, L. O'Donnell, E. R. Simpson, and M. E. E. Jones
The Phenotype of the Aromatase Knockout Mouse Reveals Dietary Phytoestrogens Impact Significantly on Testis Function
Endocrinology, August 1, 2002; 143(8): 2913 - 2921.
[Abstract] [Full Text] [PDF]

Home page
 Ann. N. Y. Acad. Sci.Home page
R. I. NICHOLSON, I. R. HUTCHESON, M. E. HARPER, J. M. KNOWLDEN, D. BARROW, R. A. McCLELLAND, H. E. JONES, A. E. WAKELING, and J.M. W. GEE
Modulation of Epidermal Growth Factor Receptor in Endocrine-Resistant, Estrogen-Receptor-Positive Breast Cancer
Ann. N.Y. Acad. Sci., June 1, 2002; 963(1): 104 - 115.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
F. Gay, P. Barath, C. Desbois-Le Peron, R. Metivier, R. Le Guevel, D. Birse, and G. Salbert
Multiple Phosphorylation Events Control Chicken Ovalbumin Upstream Promoter Transcription Factor I Orphan Nuclear Receptor Activity
Mol. Endocrinol., June 1, 2002; 16(6): 1332 - 1351.
[Abstract] [Full Text] [PDF]

Home page
 Cancer Res.Home page
S. C. Hewitt, W. P. Bocchinfuso, J. Zhai, C. Harrell, L. Koonce, J. Clark, P. Myers, and K. S. Korach
Lack of Ductal Development in the Absence of Functional Estrogen Receptor {alpha} Delays Mammary Tumor Formation Induced by Transgenic Expression of ErbB2/neu
Cancer Res., May 1, 2002; 62(10): 2798 - 2805.
[Abstract] [Full Text] [PDF]

Home page
 Toxicol SciHome page
S. L. Gadd, G. Hobbs, and M. R. Miller
Acetaminophen-Induced Proliferation of Estrogen-Responsive Breast Cancer Cells Is Associated with Increases in c-myc RNA Expression and NF-{kappa}B Activity
Toxicol. Sci., April 1, 2002; 66(2): 233 - 243.
[Abstract] [Full Text] [PDF]

Home page
 Biol. Reprod.Home page
G. Schuler, C. Wirth, U. Teichmann, K. Failing, R. Leiser, H. Thole, and B. Hoffmann
Occurrence of Estrogen Receptor {alpha} in Bovine Placentomes Throughout Mid and Late Gestation and at Parturition
Biol Reprod, April 1, 2002; 66(4): 976 - 982.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
I. T. R. Cavarretta, R. Mukopadhyay, D. M. Lonard, L. M. Cowsert, C. F. Bennett, B. W. O'Malley, and C. L. Smith
Reduction of Coactivator Expression by Antisense Oligodeoxynucleotides Inhibits ER{alpha} Transcriptional Activity and MCF-7 Proliferation
Mol. Endocrinol., February 1, 2002; 16(2): 253 - 270.
[Abstract] [Full Text] [PDF]

Home page
 Ann. N. Y. Acad. Sci.Home page
J. M. A. EMMEN and K. S. KORACH
Developing Animal Models for Analyzing SERM Activity
Ann. N.Y. Acad. Sci., December 1, 2001; 949(1): 36 - 43.
[Abstract] [Full Text] [PDF]

Home page
 CarcinogenesisHome page
G. Thordarson, A. V. Lee, M. McCarty, K. Van Horn, O. Chu, Y.-C. Chou, J. Yang, R. C. Guzman, S. Nandi, and F. Talamantes
Growth and characterization of N-methyl-N-nitrosourea-induced mammary tumors in intact and ovariectomized rats
Carcinogenesis, December 1, 2001; 22(12): 2039 - 2047.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
T. Matsuda, T. Yamamoto, A. Muraguchi, and F. Saatcioglu
Cross-talk between Transforming Growth Factor-beta and Estrogen Receptor Signaling through Smad3
J. Biol. Chem., November 9, 2001; 276(46): 42908 - 42914.
[Abstract] [Full Text] [PDF]

Home page
 Biol. Reprod.Home page
C. A. Gray, F. F. Bartol, B. J. Tarleton, A. A. Wiley, G. A. Johnson, F. W. Bazer, and T. E. Spencer
Developmental Biology of Uterine Glands
Biol Reprod, November 1, 2001; 65(5): 1311 - 1323.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
F. Demay, M. De Monti, C. Tiffoche, C. Vaillant, and M. L. Thieulant
Steroid-Independent Activation of ER by GnRH in Gonadotrope Pituitary Cells
Endocrinology, August 1, 2001; 142(8): 3340 - 3347.
[Abstract] [Full Text] [PDF]

Home page
 Clin. Cancer Res.Home page
D.-L. Lin, M. C. Whitney, Z. Yao, and E. T. Keller
Interleukin-6 Induces Androgen Responsiveness in Prostate Cancer Cells through Up-Regulation of Androgen Receptor Expression
Clin. Cancer Res., June 1, 2001; 7(6): 1773 - 1781.
[Abstract] [Full Text] [PDF]

Home page
 Biol. Reprod.Home page
K. M. Taylor, C. Chen, C. A. Gray, F. W. Bazer, and T. E. Spencer
Expression of Messenger Ribonucleic Acids for Fibroblast Growth Factors 7 and 10, Hepatocyte Growth Factor, and Insulin-Like Growth Factors and Their Receptors in the Neonatal Ovine Uterus
Biol Reprod, April 1, 2001; 64(4): 1236 - 1246.
[Abstract] [Full Text]

Home page
 Am. J. Pathol.Home page
A. O. Stemmer-Rachamimov, T. Wiederhold, G. P. Nielsen, M. James, D. Pinney-Michalowski, J. E. Roy, W. A. Cohen, V. Ramesh, and D. N. Louis
NHE-RF, a Merlin-Interacting Protein, Is Primarily Expressed in Luminal Epithelia, Proliferative Endometrium, and Estrogen Receptor-Positive Breast Carcinomas
Am. J. Pathol., January 1, 2001; 158(1): 57 - 62.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
M. B. Martin, T. F. Franke, G. E. Stoica, P. Chambon, B. S. Katzenellenbogen, B. A. Stoica, M. S. McLemore, S. E. Olivo, and A. Stoica
A Role for Akt in Mediating the Estrogenic Functions of Epidermal Growth Factor and Insulin-Like Growth Factor I
Endocrinology, December 1, 2000; 141(12): 4503 - 4511.
[Abstract] [Full Text] [PDF]

Home page
 J. Pharmacol. Exp. Ther.Home page
M. Dutertre and C. L. Smith
Molecular Mechanisms of Selective Estrogen Receptor Modulator (SERM) Action
J. Pharmacol. Exp. Ther., November 1, 2000; 295(2): 431 - 437.
[Abstract] [Full Text]

Home page
 Circ. Res.Home page
M. P. Haynes, D. Sinha, K. S. Russell, M. Collinge, D. Fulton, M. Morales-Ruiz, W. C. Sessa, and J. R. Bender
Membrane Estrogen Receptor Engagement Activates Endothelial Nitric Oxide Synthase via the PI3-Kinase-Akt Pathway in Human Endothelial Cells
Circ. Res., October 13, 2000; 87(8): 677 - 682.
[Abstract] [Full Text]

Home page
 EndocrinologyHome page
T. L. Woodward, J. Xie, J. L. Fendrick, and S. Z. Haslam
Proliferation of Mouse Mammary Epithelial Cells in Vitro: Interactions among Epidermal Growth Factor, Insulin-Like Growth Factor I, Ovarian Hormones, and Extracellular Matrix Proteins
Endocrinology, October 1, 2000; 141(10): 3578 - 3586.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
S.-H. Hong and M. L. Privalsky
The SMRT Corepressor Is Regulated by a MEK-1 Kinase Pathway: Inhibition of Corepressor Function Is Associated with SMRT Phosphorylation and Nuclear Export
Mol. Cell. Biol., September 1, 2000; 20(17): 6612 - 6625.
[Abstract] [Full Text]

Home page
 Mol. Cell. Biol.Home page
D. G. Monroe, D. F. Jin, and M. M. Sanders
Estrogen Opposes the Apoptotic Effects of Bone Morphogenetic Protein 7 on Tissue Remodeling
Mol. Cell. Biol., July 1, 2000; 20(13): 4626 - 4634.
[Abstract] [Full Text]

Home page
 Biol. Reprod.Home page
K. M. Taylor, C. A. Gray, M. M. Joyce, M. D. Stewart, F. W. Bazer, and T. E. Spencer
Neonatal Ovine Uterine Development Involves Alterations in Expression of Receptors for Estrogen, Progesterone, and Prolactin
Biol Reprod, April 1, 2000; 63(4): 1192 - 1204.
[Abstract] [Full Text]

Home page
 Cancer Res.Home page
T. Otsuki, O. Yamada, J. Kurebayashi, T. Moriya, H. Sakaguchi, H. Kunisue, K. Yata, M. Uno, Y. Yawata, and A. Ueki
Estrogen Receptors in Human Myeloma Cells
Cancer Res., March 1, 2000; 60(5): 1434 - 1441.
[Abstract] [Full Text]

Home page
 J. Clin. Endocrinol. Metab.Home page
J. Van Wyk
Insulin-Like Growth Factors and Skeletal Growth: Possibilities for Therapeutic Interventions
J. Clin. Endocrinol. Metab., December 1, 1999; 84(12): 4349 - 4354.
[Full Text]

Home page
 EndocrinologyHome page
T. W. Furlanetto, L. Q. Nguyen, and J. L. Jameson
Estradiol Increases Proliferation and Down-Regulates the Sodium/Iodide Symporter Gene in FRTL-5 Cells
Endocrinology, December 1, 1999; 140(12): 5705 - 5711.
[Abstract] [Full Text]

Home page