| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Articles |
a Institute for Research in Reproduction, Indian Council of Medical Research, Parel, Mumbai 400 012, India
The present study, to our knowledge, is the first to demonstrate presence of progesterone receptor (PR) transcript in human spermatozoa. The study shows the presence of low copy number PR mRNA in mature human spermatozoa. The PR transcript in spermatozoa was detected by reverse transcriptase-polymerase chain reaction using primers specific for the hormone binding domain and the DNA binding domain of the conventional uterine PR. Further, the cDNA sequence of the partial PR transcript from spermatozoa was found to be identical to the region spanning nucleotides 2694 to 3230 of the conventional PR full-length cDNA sequence. This study also indirectly suggests that the PR protein indeed is an intrinsic sperm protein and is not acquired through proteinaceous secretions of accessory reproductive organs.
1 Correspondence: Chander P. Puri, Institute for Research in Reproduction, Indian Council of Medical Research, Jehangir Merwanji Street, Parel, Mumbai 400 012, India. FAX: 91 22 4964853, 4139412; vichin{at}bom4.vsnl.net.in
This article has been cited by other articles:
|
|
 |
|
  R. K. Naz and R. Sellamuthu Receptors in Spermatozoa: Are They Real? J Androl, September 1, 2006; 27(5): 627 - 636. [Full Text] [PDF]
|
|
|
|
 |
|
 D Modi, C Shah, G Sachdeva, S Gadkar, D Bhartiya, and C Puri Ontogeny and cellular localization of SRY transcripts in the human testes and its detection in spermatozoa Reproduction, November 1, 2005; 130(5): 603 - 613. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 V S Patil, G Sachdeva, D N Modi, R R Katkam, D D Manjramkar, I Hinduja, and C P Puri Rab coupling protein (RCP): a novel target of progesterone action in primate endometrium J. Mol. Endocrinol., October 1, 2005; 35(2): 357 - 372. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J.P. Dadoune, A. Pawlak, M.F. Alfonsi, and J.P. Siffroi Identification of transcripts by macroarrays, RT-PCR and in situ hybridization in human ejaculate spermatozoa Mol. Hum. Reprod., February 1, 2005; 11(2): 133 - 140. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Shah, D. Modi, G. Sachdeva, S. Gadkar, and C. Puri Coexistence of Intracellular and Membrane-Bound Progesterone Receptors in Human Testis J. Clin. Endocrinol. Metab., January 1, 2005; 90(1): 474 - 483. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. M. LOSEL, E. FALKENSTEIN, M. FEURING, A. SCHULTZ, H.-C. TILLMANN, K. ROSSOL-HASEROTH, and M. WEHLING Nongenomic Steroid Action: Controversies, Questions, and Answers Physiol Rev, July 1, 2003; 83(3): 965 - 1016. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Lambard, I. Galeraud-Denis, H. Bouraima, S. Bourguiba, A. Chocat, and S. Carreau Expression of aromatase in human ejaculated spermatozoa: a putative marker of motility Mol. Hum. Reprod., March 1, 2003; 9(3): 117 - 124. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. Schwarzenbach, P. R. Manna, D. M. Stocco, G. Chakrabarti, and A. K. Mukhopadhyay Stimulatory Effect of Progesterone on the Expression of Steroidogenic Acute Regulatory Protein in MA-10 Leydig Cells Biol Reprod, March 1, 2003; 68(3): 1054 - 1063. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Gadkar, C.A. Shah, G. Sachdeva, U. Samant, and C.P. Puri Progesterone Receptor as an Indicator of Sperm Function Biol Reprod, October 1, 2002; 67(4): 1327 - 1336. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J.J. Peluso, G. Fernandez, A. Pappalardo, and B.A. White Membrane-Initiated Events Account for Progesterone's Ability to Regulate Intracellular Free Calcium Levels and Inhibit Rat Granulosa Cell Mitosis Biol Reprod, August 1, 2002; 67(2): 379 - 385. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
