| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Regular article |
a Faculty of Veterinary Medicine, University College Dublin, Ballsbridge, Dublin 4, Ireland
b Molecular Reproductive Endocrinology Laboratory, Department of Animal Science, Michigan State University, East Lansing, Michigan 48824
c School of Animal and Microbial Sciences, University of Reading, Reading RG6 2AJ, United Kingdom
ABSTRACT
A surgical procedure to aspirate follicular fluid concurrently from individual follicles from the same heifer was validated and used to determine if intrafollicular amounts of estradiol, progesterone, inhibins, activin-A, follistatins, and insulin-like growth factor binding proteins (IGFBP) differed for the future dominant compared with subordinate follicles during selection of the first wave dominant follicle. Heifers were subjected to surgery and aspiration of follicular fluid from the two or three largest follicles on Day 3 of the estrous cycle (~1.5 days after emergence). Ultrasound was used to determine the fate of each aspirated follicle after surgery. At aspiration, diameter of the future dominant and largest subordinate follicle was similar in heifers. However, estradiol was higher, whereas IGFBP-4 was lower in the future dominant compared with the largest or next largest subordinate follicles. Also, the future dominant follicle in most cohorts had the highest estradiol and lowest IGFBP-4 compared with future subordinate follicles. We concluded that: IGFBP-4 and estradiol may have key roles in determining the physiological fate of follicles during selection of the first wave dominant follicle in heifers, and that both are reliable markers to predict which follicle in a growing cohort of 5- to 8.5-mm follicles becomes dominant.
First decision: 22 December 1999.
1 Research supported by grants from USDA (90-27240-5508) and Research Excellence Funds from Michigan State University to J.J.I.; Research Stimulus Fund, Department of Agriculture and Food to J.F.R., and BBSRC (SO5760) to P.G.K.
2 Correspondence. FAX: 353 16600883; jfroche{at}vetmed.ucd.ie
3 Current address: Department of Veterinary Preclinical Studies, University of Glasgow Veterinary School, Glasgow G61 1QH, U.K.
This article has been cited by other articles:
|
|
 |
|
  M Mihm, P J Baker, L M Fleming, A M Monteiro, and P J O'Shaughnessy Differentiation of the bovine dominant follicle from the cohort upregulates mRNA expression for new tissue development genes Reproduction, February 1, 2008; 135(2): 253 - 265. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. T. Grazul-Bilska, C. Navanukraw, M. L. Johnson, K. A. Vonnahme, S. P. Ford, L. P. Reynolds, and D. A. Redmer Vascularity and expression of angiogenic factors in bovine dominant follicles of the first follicular wave J Anim Sci, August 1, 2007; 85(8): 1914 - 1922. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K E Ryan, S M Casey, M J Canty, M A Crowe, F Martin, and A C O Evans Akt and Erk signal transduction pathways are early markers of differentiation in dominant and subordinate ovarian follicles in cattle Reproduction, March 1, 2007; 133(3): 617 - 626. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S Llewellyn, R Fitzpatrick, D A Kenny, J J Murphy, R J Scaramuzzi, and D C Wathes Effect of negative energy balance on the insulin-like growth factor system in pre-recruitment ovarian follicles of post partum dairy cows Reproduction, March 1, 2007; 133(3): 627 - 639. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. J. Schweigert, B. Gericke, W. Wolfram, U. Kaisers, and J. W. Dudenhausen Peptide and protein profiles in serum and follicular fluid of women undergoing IVF Hum. Reprod., November 1, 2006; 21(11): 2960 - 2968. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M A Beg and O J Ginther Follicle selection in cattle and horses: role of intrafollicular factors. Reproduction, September 1, 2006; 132(3): 365 - 377. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Sahmi, E. S Nicola, and C. A Price Hormonal regulation of cytochrome P450 aromatase mRNA stability in non-luteinizing bovine granulosa cells in vitro. J. Endocrinol., July 1, 2006; 190(1): 107 - 115. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. M Quirk, R. G Cowan, and R. M Harman The susceptibility of granulosa cells to apoptosis is influenced by oestradiol and the cell cycle. J. Endocrinol., June 1, 2006; 189(3): 441 - 453. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Kobayashi, F. Jimenez-Krassel, Q. Li, J. Yao, R. Huang, J. J. Ireland, P. M. Coussens, and G. W. Smith Evidence that Cocaine- and Amphetamine-Regulated Transcript Is a Novel Intraovarian Regulator of Follicular Atresia Endocrinology, November 1, 2004; 145(11): 5373 - 5383. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A.C.O. Evans, J.L.H. Ireland, M.E. Winn, P. Lonergan, G.W. Smith, P.M. Coussens, and J.J. Ireland Identification of Genes Involved in Apoptosis and Dominant Follicle Development During Follicular Waves in Cattle Biol Reprod, May 1, 2004; 70(5): 1475 - 1484. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. M. Quirk, R. G. Cowan, R. M. Harman, C.-L. Hu, and D. A. Porter Ovarian follicular growth and atresia: The relationship between cell proliferation and survival J Anim Sci, January 1, 2004; 82(13_suppl): E40 - 52. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Webb, P. C. Garnsworthy, J.-G. Gong, and D. G. Armstrong Control of follicular growth: Local interactions and nutritional influences J Anim Sci, January 1, 2004; 82(13_suppl): E63 - 74. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P.J.M. Hendriksen, B.M. Gadella, P.L.A.M. Vos, E. Mullaart, T.A.M. Kruip, and S.J. Dieleman Follicular Dynamics Around the Recruitment of the First Follicular Wave in the Cow Biol Reprod, December 1, 2003; 69(6): 2036 - 2044. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Sisco, L. J. Hagemann, A. N. Shelling, and P. L. Pfeffer Isolation of Genes Differentially Expressed in Dominant and Subordinate Bovine Follicles Endocrinology, September 1, 2003; 144(9): 3904 - 3913. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. M. Rivera and J. E. Fortune Proteolysis of Insulin-Like Growth Factor Binding Proteins -4 and -5 in Bovine Follicular Fluid: Implications for Ovarian Follicular Selection and Dominance Endocrinology, July 1, 2003; 144(7): 2977 - 2987. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Jimenez-Krassel, M. E. Winn, D. Burns, J. L. H. Ireland, and J. J. Ireland Evidence for a Negative Intrafollicular Role for Inhibin in Regulation of Estradiol Production by Granulosa Cells Endocrinology, May 1, 2003; 144(5): 1876 - 1886. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. P. Wettemann, C. A. Lents, N. H. Ciccioli, F. J. White, and I. Rubio Nutritional- and suckling-mediated anovulation in beef cows J Anim Sci, February 1, 2003; 81(14_suppl_2): E48 - 59. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. M. Prado, R. P. Wettemann, L. J. Spicer, J. A. Vizcarra, and G. L. Morgan Influence of exogenous gonadotropin-releasing hormone on ovarian function in beef cows after short- and long-term nutritionally induced anovulation J Anim Sci, December 1, 2002; 80(12): 3268 - 3276. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Spears, S. Baker, V. Srsen, R. Lapping, J. Mullan, R. Nelson, and V. Allison Mouse Ovarian Follicles Secrete Factors Affecting the Growth and Development of Like-Sized Ovarian Follicles In Vitro Biol Reprod, December 1, 2002; 67(6): 1726 - 1733. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M.A. Beg, D.R. Bergfelt, K. Kot, and O.J. Ginther Follicle Selection in Cattle: Dynamics of Follicular Fluid Factors During Development of Follicle Dominance Biol Reprod, January 1, 2002; 66(1): 120 - 126. [Abstract] [Full Text]
|
|
|
|
|
|
S. J. Baker, V. Srsen, R. Lapping, and N. Spears Combined Effect of Follicle-Follicle Interactions and Declining Follicle-Stimulating Hormone on Murine Follicle Health In Vitro Biol Reprod, October 1, 2001; 65(4): 1304 - 1310. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
O.J. Ginther, M.A. Beg, D.R. Bergfelt, F.X. Donadeu, and K. Kot Follicle Selection in Monovular Species Biol Reprod, September 1, 2001; 65(3): 638 - 647. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J.E. Fortune, G.M. Rivera, A.C.O. Evans, and A.M. Turzillo Differentiation of Dominant Versus Subordinate Follicles in Cattle Biol Reprod, September 1, 2001; 65(3): 648 - 654. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G.M. Rivera, Y.A. Chandrasekher, A.C.O. Evans, L.C. Giudice, and J.E. Fortune A Potential Role for Insulin-Like Growth Factor Binding Protein-4 Proteolysis in the Establishment of Ovarian Follicular Dominance in Cattle Biol Reprod, July 1, 2001; 65(1): 102 - 111. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G.M. Rivera and J.E. Fortune Development of Codominant Follicles in Cattle Is Associated with a Follicle-Stimulating Hormone-Dependent Insulin-Like Growth Factor Binding Protein-4 Protease Biol Reprod, July 1, 2001; 65(1): 112 - 118. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E.J. Austin, M. Mihm, A.C.O. Evans, P.G. Knight, J.L.H. Ireland, J.J. Ireland, and J.F. Roche Alterations in Intrafollicular Regulatory Factors and Apoptosis During Selection of Follicles in the First Follicular Wave of the Bovine Estrous Cycle Biol Reprod, March 1, 2001; 64(3): 839 - 848. [Abstract] [Full Text]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
