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Biology of Reproduction 63, 1575B-1579 (2000)
© 2000 Society for the Study of Reproduction, Inc.


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Human Fetal Membranes: Their Preterm Premature Rupture1

Gillian D. Bryant-Greenwood2,a, and Lynnae K. Millara

a Pacific Biomedical Research Center, University of Hawaii, Honolulu, Hawaii 96822

At the 1999 annual meeting of the Society for the Study of Reproduction there were three speakers in the minisymposium entitled ``I've got to get out of here: fetal-maternal interactions involved in parturition''. The primary focus was on research progress in understanding the mechanisms involved in human parturition. Although the title of the symposium emphasized the need to ``get out'', there was considerable emphasis on understanding the problem of ``getting out too early'' or preterm birth. While preterm birth is unusual in most species, it is of major clinical importance in the human. The data presented by one of the speakers is reviewed here with a focus on preterm labor and preterm premature rupture of the fetal membranes as mechanisms involved in the diverse pathology of preterm birth.

First decision: 10 May 2000.

1 This work was supported by NIH grants HD06633 and HD24314 and grants to the University of Hawaii and Kapiolani Medial Center under the Research Centers in Minority Institutions Program of the NCRR (RR1A1-03061 and RR-11091).

2 Correspondence: G.D. Bryant-Greenwood, Department of Cell and Molecular Biology, University of Hawaii, 1960 East-West Road, Honolulu, HI 96822. FAX: 808 956 9481; gbg{at}pbrc.hawaii.edu







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