Biol Reprod Keystone Symposia Conference on Frontiers in Reproductive Biology & Regulation of Fertility.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

BOR - Papers in Press, published online ahead of print January 22, 2003.
Biol Reprod 2003, 10.1095/biolreprod.102.012955
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
68/6/2172    most recent
biolreprod.102.012955v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by King, A. H.
Right arrow Articles by Archibald, A. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by King, A. H.
Right arrow Articles by Archibald, A. L.
Agricola
Right arrow Articles by King, A. H.
Right arrow Articles by Archibald, A. L.
BIOLOGY OF REPRODUCTION 68, 2172–2179 (2003)
DOI: 10.1095/biolreprod.102.012955
© 2003 by the Society for the Study of Reproduction, Inc.

Pregnancy

Mapping Quantitative Trait Loci Affecting Female Reproductive Traits on Porcine Chromosome 81

Annemarie H. King2,4, Zhihua Jiang5, John P. Gibson3,5, Chris S. Haley4, and Alan L. Archibald4

Roslin Institute (Edinburgh),4 Roslin, Midlothian, EH25 9PS, United Kingdom Centre for Genetic Improvement of Livestock,5 Department of Animal and Poultry Science, University of Guelph, Guelph, Canada N1G 2W1

An understanding of the genetic control of porcine female reproductive performance would offer the opportunity to utilize natural variation and improve selective breeding programs through marker-assisted selection. The Chinese Meishan is one of the most prolific pig breeds known, farrowing three to five more viable piglets per litter than the European Large White breed. This difference in prolificacy is attributed to the Meishan's superior prenatal survival levels. The present study utilized a three-generation cross in which the founder grandparental animals were purebred Meishan and Large White pigs in a scan for quantitative trait loci (QTL) on porcine chromosome 8 (SSC8) associated with reproductive performance. Reproductive traits, including number of corpora lutea (ovulation rate), teat number, litter size, and prenatal survival, were recorded for as many as 220 F2 females. Putative QTL for the related traits of litter size and prenatal survival were identified at the distal end of the long arm of SSC8. A physiological candidate gene, SPP1, was found to lie within the 95% confidence interval of these QTL. A suggestive QTL for teat number was revealed on the short arm of SSC8. The present study demonstrates, to our knowledge, the first independent confirmation of QTL for fecundity on SSC8, and these QTL regions provide a crucial starting point in the search for the causal genetic variants.

1 The reproductive QTL project was funded by the U.K. Ministry of Agriculture, Fisheries and Food. A.H.K. was supported by a BBSRC Industrial CASE studentship with Sygen/PIC as the industrial partner; the Natural Sciences and Engineering Research Council of Canada and the GENEX Swine Group, Canada, also provided financial assistance. A.H.K. and Z.J. contributed equally to the genotyping work.

2 Correspondence: Annemarie King, Department of Genomics and Bioinformatics, Roslin Institute, Roslin, Midlothian, EH25 9PS, U.K. FAX: 44 131 440 0434; annemarie.king{at}bbsrc.ac.uk

3 Current address: International Livestock Research Institute, Kenya






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2003 by the Society for the Study of Reproduction.