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This Article Full Text Full Text (PDF) All Versions of this Article: 69/6/1951    most recent biolreprod.103.017780v1 Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal My Folders Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Bayley, M. Articles by Baatrup, E. Search for Related Content PubMed PubMed Citation Articles by Bayley, M. Articles by Baatrup, E. Agricola Articles by Bayley, M. Articles by Baatrup, E.

The Effects of Vinclozolin, an Anti-Androgenic Fungicide, on Male Guppy Secondary Sex Characters and Reproductive Success¹

Department of Zoology, Institute of Biological Sciences, University of Aarhus, DK-8000 Aarhus C, Denmark

Despite the enormous volume of research concerning the various effects of chemicals with endocrine-disrupting properties in fish, there is still very little evidence that endocrine disruption can adversely affect individual fertility and, hence, pose problems for the population. In the present study, guppies (Poecilia reticulata) were fed with the anti-androgenic fungicide vinclozolin at concentrations ranging from 1.8 to 180 mg/kg from 8–14 wk of age. Male sperm count and the intensity of his sexual display behavior were significantly reduced in treatment groups, which was in line with the results of previous studies. Here, we show further that these impairments translate into reduced fertility, measured as the size of the female's first clutch. Also, this reduced fertility was correlated to the male sperm count, but not to the intensity of the male sexual display. Finally, by crossing exposed with unexposed animals, we show that the adverse effect of vinclozolin on reproduction is mediated through the male alone.

¹ Financed by a grant from the Danish Natural Sciences Research Council.

² Correspondence: Department of Zoology, Institute of Biological Sciences, University of Aarhus, Building 135, Ole Worms Allé, Dk-8000 Aarhus C, Denmark. FAX: ++45 86125175; mark.bayley{at}biology.au.dk

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