| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Reproductive Endocrinology Laboratory, Department of Animal Science,3 Michigan State University, East Lansing, Michigan 48824
School of Animal and Microbial Sciences,4 University of Reading, Reading RG6 2AJ, United Kingdom
The extent, causes, and physiological significance of the variation in number of follicles growing during ovarian follicular waves in human beings and cattle are unknown. Therefore, the present study examined the variability and repeatability in numbers of follicles 3 mm or greater in diameter during the follicular waves in bovine estrous cycles, and we determined if the variation in number of follicles during waves was associated with alterations in secretion of FSH, estradiol, inhibin, and insulin-like growth factor I (IGF-I). Dairy cattle were subjected to twice-daily ultrasound analysis to count total number of antral follicles 3 mm or greater in diameter throughout 138 different follicular waves. In another study, blood samples were taken at frequent intervals from cows that consistently had low or very high numbers of follicles during waves and were subjected to immunoassays. Results indicate the following: First, despite an approximately sevenfold variation in number of follicles during waves among animals and marked differences in age, stage of lactation, and season of the year, a very highly repeatable (0.95) number of follicles 3 mm or greater in diameter is maintained during the ovulatory and nonovulatory follicular waves of individuals. Second, variation in number of follicles 3 mm or greater in diameter during waves and the inverse association of number of follicles during waves with FSH are not directly explained by alterations in the patterns of secretion of estradiol, inhibin, or IGF-I. Third, ovarian ultrasound analysis can be used reliably by investigators to identify cattle that consistently have low or high numbers of follicles during waves, thus providing a novel experimental model to determine the causes and physiological significance of the high variation in antral follicle number during follicular waves among single-ovulating species, such as cattle or humans.
estradiol, follicle, follicle-stimulating hormone, follicular development, inhibin
2 Correspondence. FAX: 517-353-3149; Ireland{at}msu.edu
This article has been cited by other articles:
|
|
 |
|
  R. A. Cushman, M. F. Allan, L. A. Kuehn, W. M. Snelling, A. S. Cupp, and H. C. Freetly Evaluation of antral follicle count and ovarian morphology in crossbred beef cows: Investigation of influence of stage of the estrous cycle, age, and birth weight J Anim Sci, June 1, 2009; 87(6): 1971 - 1980. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. Jimenez-Krassel, J.K. Folger, J.L.H. Ireland, G.W. Smith, X. Hou, J.S. Davis, P. Lonergan, A.C.O. Evans, and J.J. Ireland Evidence That High Variation in Ovarian Reserves of Healthy Young Adults Has a Negative Impact on the Corpus Luteum and Endometrium During Estrous Cycles in Cattle Biol Reprod, June 1, 2009; 80(6): 1272 - 1281. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H F Irving-Rodgers, M L Harland, T R Sullivan, and R J Rodgers Studies of granulosa cell maturation in dominant and subordinate bovine follicles: novel extracellular matrix focimatrix is co-ordinately regulated with cholesterol side-chain cleavage CYP11A1 Reproduction, May 1, 2009; 137(5): 825 - 834. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J.J. Ireland, A.E. Zielak-Steciwko, F. Jimenez-Krassel, J. Folger, A. Bettegowda, D. Scheetz, S. Walsh, F. Mossa, P.G. Knight, G.W. Smith, et al. Variation in the Ovarian Reserve Is Linked to Alterations in Intrafollicular Estradiol Production and Ovarian Biomarkers of Follicular Differentiation and Oocyte Quality in Cattle Biol Reprod, May 1, 2009; 80(5): 954 - 964. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P C Garnsworthy, A A Fouladi-Nashta, G E Mann, K D Sinclair, and R Webb Effect of dietary-induced changes in plasma insulin concentrations during the early post partum period on pregnancy rate in dairy cows Reproduction, April 1, 2009; 137(4): 759 - 768. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Rico, S. Fabre, C. Medigue, N. d. Clemente, F. Clement, M. Bontoux, J.-L. Touze, M. Dupont, E. Briant, B. Remy, et al. Anti-Mullerian Hormone Is an Endocrine Marker of Ovarian Gonadotropin-Responsive Follicles and Can Help to Predict Superovulatory Responses in the Cow Biol Reprod, January 1, 2009; 80(1): 50 - 59. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J.L.H. Ireland, D. Scheetz, F. Jimenez-Krassel, A.P.N. Themmen, F. Ward, P. Lonergan, G.W. Smith, G.I. Perez, A.C.O. Evans, and J.J. Ireland Antral Follicle Count Reliably Predicts Number of Morphologically Healthy Oocytes and Follicles in Ovaries of Young Adult Cattle Biol Reprod, December 1, 2008; 79(6): 1219 - 1225. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. C. Garnsworthy, A. Lock, G. E. Mann, K. D. Sinclair, and R. Webb Nutrition, Metabolism, and Fertility in Dairy Cows: 1. Dietary Energy Source and Ovarian Function J Dairy Sci, October 1, 2008; 91(10): 3814 - 3823. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. C. Garnsworthy, A. Lock, G. E. Mann, K. D. Sinclair, and R. Webb Nutrition, Metabolism, and Fertility in Dairy Cows: 2. Dietary Fatty Acids and Ovarian Function J Dairy Sci, October 1, 2008; 91(10): 3824 - 3833. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Monniaux, N. d. Clemente, J.-L. Touze, C. Belville, C. Rico, M. Bontoux, J.-Y. Picard, and S. Fabre Intrafollicular Steroids and Anti-Mullerian Hormone During Normal and Cystic Ovarian Follicular Development in the Cow Biol Reprod, August 1, 2008; 79(2): 387 - 396. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. S Malhi, G. P Adams, R. J Mapletoft, and J. Singh Oocyte developmental competence in a bovine model of reproductive aging Reproduction, August 1, 2007; 134(2): 233 - 239. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 JJ. Ireland, F. Ward, F. Jimenez-Krassel, J.L.H. Ireland, G.W. Smith, P. Lonergan, and A.C.O. Evans Follicle numbers are highly repeatable within individual animals but are inversely correlated with FSH concentrations and the proportion of good-quality embryos after ovarian stimulation in cattle Hum. Reprod., June 1, 2007; 22(6): 1687 - 1695. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. M. Bello, J. P. Steibel, and J. R. Pursley Optimizing ovulation to first GnRH improved outcomes to each hormonal injection of ovsynch in lactating dairy cows. J Dairy Sci, September 1, 2006; 89(9): 3413 - 3424. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
