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Biology of Reproduction, Vol 8, 38-42, Copyright © 1973 by Society for the Study of Reproduction

A Polypeptide from Oviductal Contents which Influences Ovarian Function

HARRY A. KENT JR. 1

1 Department of Zoology, University of Georgia, Athens, Georgia 30601


Bilateral removal of the oviducts causes a significant decrease in the numbers of ovulations occurring in nonbred female hamsters, as monitored by numbers of corpora hemorrhagica. A factor from oviductal contents, taken early on day 3 pc from progravid female hamsters, will decrease ovarian function in nonbred female hamsters when injected sc. The biologically active fraction from oviductal contents (of progravid hamsters) appears to be a polypeptide with a molecular weight below 700. It is assumed that the factor from oviductal contents influences the stroma of of the oviduct which, in turn, influences ovarian function.

Submitted on April 8, 1971






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Copyright © 1973 by the Society for the Study of Reproduction.