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BIOLOGY OF REPRODUCTION 79, 172–178 (2008)
DOI: 10.1095/biolreprod.108.070789
© 2008 by the Society for the Study of Reproduction, Inc.

research-article

EDITORIAL Germ Cells from Stem Cells

John Eppig and Mary Ann Handel, Editors-in-Chief, Biology of Reproduction

In April 2008, outside of Cambridge, England, The Hinxton Group convened an international consortium to discuss an exciting new area of research that has emerged over the last few years: the production of germ cells from pluripotent stem cells in vitro. Although functional eggs or sperm have not yet been produced in vitro from either embryonic stem (ES) cells or induced pluripotent stem (iPS) cells, progress has been tantalizing. This research opens new opportunities for studies on the development of germ cells and prospects for clinical applications. The goal of the Hinxton Group was to provide conceptual framework and guiding principles for policy makers, and to this end, "A Consensus Statement: Science, Ethics and Policy Challenges of Pluripotent Stem Cell-Derived Gametes" emerged after three days of discussion and debate. This statement, reproduced here verbatim, should stimulate interest and discussion throughout the community of reproductive and developmental biologists and provide a framework for societal debate.

Copyright 2008 by The Hinxton Group; reprinted here with permission.





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