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BOR - Papers in Press, published online ahead of print October 25, 2006.
Biol Reprod 2006, 10.1095/biolreprod.106.056259
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biolreprod.106.056259v1
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Submitted August 6, 2006
Returned for revision August 23, 2006
Accepted October 24, 2006

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Sex-Sorted Sperm and Fertility: An Alternative View

Valerie J. Grant * and Lawrence W. Chamley

* To whom correspondence should be addressed. E-mail: vj.grant{at}auckland.ac.nz.

Abstract
Although contemporary methods of physically separating X- from Y-chromosomebearing spermatozoa are now very efficient, overall fertility rates following the use of sex-sorted sperm are not as impressive, in spite of many attempts to improve them. At the same time, there are suggestions from evolutionary biology, and from sex allocation theory in particular, that there may need to be a modification to the "chance" theory of sex determination in mammals. This is because it now appears the mammalian female could have some influence on the sex of her offspring, and furthermore, that this influence could be pre-conceptual. If so, this could go some way towards accounting for the putative inefficiencies in fertilisation following insemination with sex-sorted sperm.

Key words: Gamete Biology • Assisted Reproductive Technology • Fertilization • Sperm





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