HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

COVER:
From Analysis of hypomorphic KitlSl mutants suggests different requirements for KITL in proliferation and migration of mouse primordial germ cells by Aparna Mahakali Zama, F. Parker Hudson III, and Mary A. Bedell (Biology of Reproduction 73:639–647, 2005). Mouse embryos at 10.5 days of gestation were taken from a pregnant mouse that had been injected with BrdU, which incorporates into DNA of all cells undergoing S phase. Sections from these embryos were stained with an anti-BrdU antibody (green fluorescence) and for alkaline phosphatase activity (red fluorescence), which is a marker specific for primordial germ cells, and examined under a laser scanner confocal microscope. The nuclei of all cells in S phase are green. Non-proliferating primordial germ cells are red with unstained nuclei, while proliferating primordial germ cells are red and have green nuclei.

Cover design and layout: Jane Tenenbaum, Tenenbaum Design, Madison, Wisconsin.