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COVER: From "Catsper3 and Catsper4 Encode Two Cation Channel-Like Proteins Exclusively Expressed in the Testis" by Jing-Ling Jin, Alan M. O'Doherty, Shouhua Wang, Huili Zheng, Kenton M. Sanders, and Wei Yan (Biol Reprod 2005; 73:1235-1242). A high-power (400×), dark-field image shows Catsper3 mRNA localization in the mouse testis by in situ hybridization. Catsper3 mRNA hybridization signals (silver grains) are confined to round spermatids, and autofluorescence of testicular cells are in orange. Cover design and layout: Jane Tenenbaum, Tenenbaum Design, Madison, Wisconsin. Biology of Reproduction is printed with soy-based inks on acid-free paper by Allen Press, Inc., Lawrence, Kansas.