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COVER: From "Alterations in Gene Expression in the Caput Epididymides of Nonobstructive Azoospermic Men" by Evemie Dubé, Louis Hermo, Peter T.K. Chan, and Daniel G. Cyr. Biol Reprod 2008; 78:342-351. Published in BOR-Papers In Press October 10, 2007; DOI 10.1095/biolreprod.107.062760. Dubé et al. report the occurrence of alterations in gene expression in the caput epididymidis of infertile nonobstructive azoospermic versus fertile patients. Cover image shows the localization of the tight junctional protein Claudin 1 (in brown) along the lateral plasma membrane and tight junction between principal and basal cells of the caput epididymidis of a fertile patient. Cover design and layout: Jane Tenenbaum, Tenenbaum Design, Cambridge, Massachusetts. Biology of Reproduction is printed with soy-based inks on acid-free paper by Allen Press, Inc., Lawrence, Kansas.