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COVER: From "Beta-Defensin 126 on the Surface of Macaque Sperm Mediates Attachment of Sperm to Oviductal Epithelia" by Theodore L. Tollner, Ashley I. Yudin, Alice F. Tarantal, Cathy A. Treece, James W. Overstreet, and Gary N. Cherr. Biol Reprod 2008: 78:400-412. Published online in BOR-Papers In Press 14 November 2007: DOI 10.1095/biorepod.107.064071. High magnification confocal microscopy of epithelial sheets extracted from peri-ovulatory oviducts labeled with monkey sperm surface protein DEFB126 in situ demonstrates that DEFB126 localizes only to apical regions of secretory cells. The signal for DEFB126 (red) is superimposed on the differential interference contrast image. The labeling pattern is consistent with the distribution of sperm binding to oviductal epithelia in vitro as observed by both confocal and video micrography: 96% of the sperm attached to the epithelium bind (via the head) to secretory cells. Few sperm bind to ciliated cells. Cover design and layout: Jane Tenenbaum, Tenenbaum Design, Cambridge, Massachusetts. Biology of Reproduction is printed with soy-based inks on acid-free paper by Allen Press, Inc., Lawrence, Kansas.